Comparative Study
doi: 10.1039/c5lc01498k.
Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC
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- PMID: 27040493
- DOI: 10.1039/c5lc01498k
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Comparative Study
Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC
Lab Chip.
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Abstract
Cyclic olefin copolymer (COC) is widely used in microfluidics due to its UV-transparency, its biocompatibility and high chemical resistance. Here we present a fast and cost-effective solvent bonding technique, which allows for the efficient bonding of protein-patterned COC structures. The bonding process is carried out at room temperature and takes less than three minutes. Enzyme activity is retained upon bonding and microstructure deformation does not occur.
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