The importance of hydration in wound healing: reinvigorating the clinical perspective
- PMID: 26947692
- DOI: 10.12968/jowc.2016.25.3.122
The importance of hydration in wound healing: reinvigorating the clinical perspective
Abstract
Balancing skin hydration levels is important as any disruption in skin integrity will result in disturbance of the dermal water balance. The discovery that a moist environment actively supports the healing response when compared with a dry environment highlights the importance of water and good hydration levels for optimal healing. The benefits of 'wet' or 'hyper-hydrated' wound healing appear similar to those offered by moist over a dry environment. This suggests that the presence of free water may not be detrimental to healing, but any adverse effects of wound fluid on tissues is more likely related to the biological components contained within chronic wound exudate, for example elevated protease levels. Appropriate dressings applied to wounds must not only be able to absorb the exudate, but also retain this excess fluid together with its protease solutes, while concurrently preventing desiccation. This is particularly important in the case of chronic wounds where peri-wound skin barrier properties are compromised and there is increased permeation across the injured skin. This review discusses the importance of appropriate levels of hydration in skin, with a particular focus on the need for optimal hydration levels for effective healing. Declaration of interest: This paper was supported by Paul Hartmann Ltd. The authors have provided consultative services to Paul Hartmann Ltd.
Keywords: hydration; moist wound healing; wound fluid; wound healing.
Similar articles
-
Wound healing and hyper-hydration: a counterintuitive model.J Wound Care. 2016 Feb;25(2):68, 70-5. doi: 10.12968/jowc.2016.25.2.68. J Wound Care. 2016. PMID: 26878298
-
The use of Flivasorb in highly exuding wounds.Br J Nurs. 2009 Aug 13-Sep 9;18(15):S38, S40-2. doi: 10.12968/bjon.2009.18.Sup5.43572. Br J Nurs. 2009. PMID: 19718000 Review.
-
Exudate and care of the peri-wound skin.Nurs Stand. 2004 Oct 27-Nov 2;19(7):62, 64, 66 passim. doi: 10.7748/ns2004.10.19.7.62.c3737. Nurs Stand. 2004. PMID: 15551919 Review.
-
An introduction to absorbent dressings.Br J Community Nurs. 2014 Dec;Suppl Wound Care:S28-30. doi: 10.12968/bjcn.2014.19.Sup12.S28. Br J Community Nurs. 2014. PMID: 25478853 Review.
-
A clinical case-series evaluation of a superabsorbent dressing on exuding wounds.J Wound Care. 2012 Nov;21(11):574, 576-80. doi: 10.12968/jowc.2012.21.11.574. J Wound Care. 2012. PMID: 23413497
Cited by
-
Prevention of excessive scar formation using nanofibrous meshes made of biodegradable elastomer poly(3-hydroxybutyrate-co-3-hydroxyvalerate).J Tissue Eng. 2020 Aug 23;11:2041731420949332. doi: 10.1177/2041731420949332. eCollection 2020 Jan-Dec. J Tissue Eng. 2020. PMID: 32922720 Free PMC article.
-
Nitric Oxide-Releasing Thermoresponsive Pluronic F127/Alginate Hydrogel for Enhanced Antibacterial Activity and Accelerated Healing of Infected Wounds.Pharmaceutics. 2020 Sep 28;12(10):926. doi: 10.3390/pharmaceutics12100926. Pharmaceutics. 2020. PMID: 32998349 Free PMC article.
-
Probing Skin Barrier Recovery on Molecular Level Following Acute Wounds: An In Vivo/Ex Vivo Study on Pigs.Biomedicines. 2021 Mar 31;9(4):360. doi: 10.3390/biomedicines9040360. Biomedicines. 2021. PMID: 33807251 Free PMC article.
-
Multifunctional Nanofibrous Dressing with Antimicrobial and Anti-Inflammatory Properties Prepared by Needle-Free Electrospinning.Pharmaceutics. 2021 Sep 21;13(9):1527. doi: 10.3390/pharmaceutics13091527. Pharmaceutics. 2021. PMID: 34575602 Free PMC article.
-
BSA Binding and Aggregate Formation of a Synthetic Amino Acid with Potential for Promoting Fibroblast Proliferation: An In Silico, CD Spectroscopic, DLS, and Cellular Study.Biomolecules. 2024 May 14;14(5):579. doi: 10.3390/biom14050579. Biomolecules. 2024. PMID: 38785986 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical