Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells

doi:10.1016/j.coi.2015.11.008

Review

. 2016 Feb:38:86-93.

doi: 10.1016/j.coi.2015.11.008. Epub 2015 Dec 29.

Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells

Nicholas D Huntington¹, Sabrina Carpentier², Eric Vivier³, Gabrielle T Belz⁴

Affiliations

¹ The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia. Electronic address: huntington@wehi.edu.au.
² MI-mAbs, Marseille 13288, France.
³ Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University UM2, Inserm, U1104, CNRS UMR7280, Marseille 13288, France; Immunologie, Hôpital de la Conception, Assistance Publique - Hôpitaux de Marseille, Marseille 13385, France.
⁴ The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia. Electronic address: belz@wehi.edu.au.

PMID: 26736074
DOI: 10.1016/j.coi.2015.11.008

Review

Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells

Nicholas D Huntington et al. Curr Opin Immunol. 2016 Feb.

. 2016 Feb:38:86-93.

doi: 10.1016/j.coi.2015.11.008. Epub 2015 Dec 29.

Authors

Nicholas D Huntington¹, Sabrina Carpentier², Eric Vivier³, Gabrielle T Belz⁴

Affiliations

¹ The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia. Electronic address: huntington@wehi.edu.au.
² MI-mAbs, Marseille 13288, France.
³ Centre d'Immunologie de Marseille-Luminy, Aix-Marseille University UM2, Inserm, U1104, CNRS UMR7280, Marseille 13288, France; Immunologie, Hôpital de la Conception, Assistance Publique - Hôpitaux de Marseille, Marseille 13385, France.
⁴ The Walter and Eliza Hall Institute of Medical Research, and Department of Medical Biology, University of Melbourne, Victoria 3052, Australia; Department of Medical Biology, University of Melbourne, Parkville 3010, Australia. Electronic address: belz@wehi.edu.au.

PMID: 26736074
DOI: 10.1016/j.coi.2015.11.008

Abstract

Protection of epithelial and mucosal surfaces is required for survival. The recent discovery of a diverse array of innate lymphoid cells that lie immediately beneath these surfaces has unexpectedly uncovered an entire defense system distinct from the adaptive system essential to protect these barriers. This multilayered design provides a robust system through coupling of two highly complementary networks to ensure immune protection. Here, we discuss the similarities in the hardwiring and diversification of innate lymphoid cells and T cells during mammalian immune responses.

PubMed Disclaimer

Cited by

Graft-Infiltrating Macrophages Adopt an M2 Phenotype and Are Inhibited by Purinergic Receptor P2X7 Antagonist in Chronic Rejection.
Wu C, Zhao Y, Xiao X, Fan Y, Kloc M, Liu W, Ghobrial RM, Lan P, He X, Li XC. Wu C, et al. Am J Transplant. 2016 Sep;16(9):2563-73. doi: 10.1111/ajt.13808. Epub 2016 May 2. Am J Transplant. 2016. PMID: 27575724 Free PMC article.
Insights into the tumor microenvironment of B cell lymphoma.
Ng WL, Ansell SM, Mondello P. Ng WL, et al. J Exp Clin Cancer Res. 2022 Dec 29;41(1):362. doi: 10.1186/s13046-022-02579-9. J Exp Clin Cancer Res. 2022. PMID: 36578079 Free PMC article. Review.
Isolation and Identification of Innate Lymphoid Cells (ILCs) for Immunotoxicity Testing.
Tait Wojno ED, Beamer CA. Tait Wojno ED, et al. Methods Mol Biol. 2018;1803:353-370. doi: 10.1007/978-1-4939-8549-4_21. Methods Mol Biol. 2018. PMID: 29882149 Free PMC article.
Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later.
Hajishengallis G, Korostoff JM. Hajishengallis G, et al. Periodontol 2000. 2017 Oct;75(1):116-151. doi: 10.1111/prd.12181. Periodontol 2000. 2017. PMID: 28758305 Free PMC article. Review.
Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs.
Gil-Cruz C, Perez-Shibayama C, Onder L, Chai Q, Cupovic J, Cheng HW, Novkovic M, Lang PA, Geuking MB, McCoy KD, Abe S, Cui G, Ikuta K, Scandella E, Ludewig B. Gil-Cruz C, et al. Nat Immunol. 2016 Dec;17(12):1388-1396. doi: 10.1038/ni.3566. Epub 2016 Oct 31. Nat Immunol. 2016. PMID: 27798617 Free PMC article.

See all "Cited by" articles

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- ClinicalKey
- Elsevier Science
Other Literature Sources
- The Lens - Patent Citations Database
- scite Smart Citations

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells

Affiliations

Innate lymphoid cells: parallel checkpoints and coordinate interactions with T cells

Authors

Affiliations

Abstract

Similar articles

Cited by

Publication types

MeSH terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources