Immunotherapy Not Working? Check Your Microbiota
- PMID: 26678336
- DOI: 10.1016/j.ccell.2015.11.010
Immunotherapy Not Working? Check Your Microbiota
Abstract
Gut microbes have ascended to prominence as key modulators of host immunity, raising the possibility that they could influence the outcome of cancer immunotherapy. Two recent studies address this question by identifying specific gut-resident bacteria as drivers of checkpoint blockade immunotherapy in pre-clinical tumor models.
Copyright © 2015 Elsevier Inc. All rights reserved.
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