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. 2016 Mar;93(3):263-5.
doi: 10.1016/j.contraception.2015.11.005. Epub 2015 Nov 11.

Relationship between etonogestrel level and BMI in women using the contraceptive implant for more than 1 year

Kathleen M Morrell  1 , Serge Cremers  2 , Carolyn L Westhoff  3 , Anne R Davis  4
Affiliations

Relationship between etonogestrel level and BMI in women using the contraceptive implant for more than 1 year

Kathleen M Morrell et al. Contraception. 2016 Mar.

Abstract

Progestin-only contraceptive methods, including the 3-year, single-rod etonogestrel (ENG) implant, may be preferred for obese women to avoid additional estrogen-related thrombosis risk; however, whether obese women receive an ENG sufficient dose to suppress ovulation is understudied. Our analysis expands on the limited information currently available by studying ENG levels related to body mass index (BMI) in a community sample of primarily Hispanic women. This cross-sectional, descriptive study of 52 long-term implant users found comparable ENG levels across a wide BMI range (p=.1). These results further support that ENG levels are independent of BMI through 3 years of implant use and are thus reassuring that ENG implants will be effective for women of all BMIs.

Trial registration: ClinicalTrials.gov NCT01855620.

Keywords: Contraception; Etonogestrel; Implant; Obesity.

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