[Kampo medicine (rikkunshito)]
- PMID: 26165077
[Kampo medicine (rikkunshito)]
Abstract
Gastroesophageal reflux disease (GERD), an acid-related disease, is usually treated with acid inhibitory drugs including proton pump inhibitor (PPI) according to the clinical practice guidelines for GERD in Japan. However, it is recognized that there are some GERD patients who are resistant to PPI treatment. There are some evidences that various traditional medicines especially for rikkunshito are often combined with Western medicines and prescribed for patients with PPI-refractory GERD at that time. Accordingly, rikkunshito may be useful for treating PPI-refractory GERD via its proper functions such as regulation of gastorintestinal motility and physiological integrity for acid exposure to the esophageal mucosa, because rikkunshito has no inhibitory action on gastric acid secretion.
Similar articles
-
Efficacy of Rikkunshito, a traditional Japanese medicine (Kampo), in treating functional dyspepsia.Intern Med. 2010;49(20):2195-202. doi: 10.2169/internalmedicine.49.3803. Epub 2010 Oct 15. Intern Med. 2010. PMID: 20962437 Clinical Trial.
-
Rikkunshito improves symptoms in PPI-refractory GERD patients: a prospective, randomized, multicenter trial in Japan.J Gastroenterol. 2012 Mar;47(3):284-92. doi: 10.1007/s00535-011-0488-5. Epub 2011 Nov 15. J Gastroenterol. 2012. PMID: 22081052 Clinical Trial.
-
Kampo medicines for gastrointestinal tract disorders: a review of basic science and clinical evidence and their future application.J Gastroenterol. 2013 Apr;48(4):452-62. doi: 10.1007/s00535-013-0788-z. Epub 2013 Mar 16. J Gastroenterol. 2013. PMID: 23503839 Free PMC article. Review.
-
Clinical characteristics of elderly patients with proton pump inhibitor-refractory non-erosive reflux disease from the G-PRIDE study who responded to rikkunshito.BMC Gastroenterol. 2014 Jul 2;14:116. doi: 10.1186/1471-230X-14-116. BMC Gastroenterol. 2014. PMID: 24990161 Free PMC article. Clinical Trial.
-
Beneficial effects of rikkunshito, a Japanese kampo medicine, on gastrointestinal dysfunction and anorexia in combination with Western drug: a systematic review.Evid Based Complement Alternat Med. 2014;2014:519035. doi: 10.1155/2014/519035. Epub 2014 Mar 20. Evid Based Complement Alternat Med. 2014. PMID: 24778703 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources