doi: 10.1016/0014-5793(89)81667-9.
HSV infection induces increased transcription of Alu repeated sequences by RNA polymerase III
Affiliations
- PMID: 2557237
- DOI: 10.1016/0014-5793(89)81667-9
Item in Clipboard
HSV infection induces increased transcription of Alu repeated sequences by RNA polymerase III
FEBS Lett.
.
Free article
Abstract
The Alu family of repeated sequences is transcribed by both RNA polymerase II and RNA polymerase III. In cells infected with HSV, transcription by polymerase III increases while transcription by polymerase II decreases. By using virus strains carrying mutations in the genes encoding individual regulatory proteins, we have shown that this effect is dependent upon the immediate-early protein ICP27 and occurs by a process distinct from those which regulate viral gene expression. This is the first example of increased transcription of endogenous cellular sequences by RNA polymerase III during infection with a DNA virus.
Similar articles
-
The herpes simplex virus immediate-early protein ICP27 stimulates the transcription of cellular Alu repeated sequences by increasing the activity of transcription factor TFIIIC.Biochem J. 1992 Jun 15;284 ( Pt 3)(Pt 3):667-73. doi: 10.1042/bj2840667. Biochem J. 1992. PMID: 1320373 Free PMC article.
-
Activation of RNA polymerase III transcription of human Alu elements by herpes simplex virus.Virology. 1994 Jul;202(1):408-17. doi: 10.1006/viro.1994.1357. Virology. 1994. PMID: 8009851
-
Analysis of transcription of the human Alu family ubiquitous repeating element by eukaryotic RNA polymerase III.Nucleic Acids Res. 1981 Dec 11;9(23):6439-56. doi: 10.1093/nar/9.23.6439. Nucleic Acids Res. 1981. PMID: 6275362 Free PMC article.
-
Surprises in polymerase III transcription.Cell. 1988 Jan 29;52(2):153-4. doi: 10.1016/0092-8674(88)90500-4. Cell. 1988. PMID: 2449281 Review. No abstract available.
-
Common mechanisms of promoter recognition by RNA polymerases II and III.Trends Genet. 1989 Apr;5(4):122-6. doi: 10.1016/0168-9525(89)90043-7. Trends Genet. 1989. PMID: 2658227 Review.
Cited by
-
Retrotransposon life cycle and its impacts on cellular responses.RNA Biol. 2024 Jan;21(1):11-27. doi: 10.1080/15476286.2024.2409607. Epub 2024 Oct 13. RNA Biol. 2024. PMID: 39396200 Free PMC article. Review.
-
RNA polymerase III promoter and terminator elements affect Alu RNA expression.Nucleic Acids Res. 1995 May 25;23(10):1750-7. doi: 10.1093/nar/23.10.1750. Nucleic Acids Res. 1995. PMID: 7540287 Free PMC article.
-
A CBF5 mutation that disrupts nucleolar localization of early tRNA biosynthesis in yeast also suppresses tRNA gene-mediated transcriptional silencing.Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13108-13. doi: 10.1073/pnas.240454997. Proc Natl Acad Sci U S A. 2000. PMID: 11069303 Free PMC article.
-
Cell stress and translational inhibitors transiently increase the abundance of mammalian SINE transcripts.Nucleic Acids Res. 1995 May 25;23(10):1758-65. doi: 10.1093/nar/23.10.1758. Nucleic Acids Res. 1995. PMID: 7784180 Free PMC article.
-
Host Noncoding Retrotransposons Induced by DNA Viruses: a SINE of Infection?J Virol. 2017 Nov 14;91(23):e00982-17. doi: 10.1128/JVI.00982-17. Print 2017 Dec 1. J Virol. 2017. PMID: 28931686 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
