Microbiota, the immune system, black moods and the brain-melancholia updated

doi:10.3389/fnhum.2014.00720

. 2014 Sep 15:8:720.

doi: 10.3389/fnhum.2014.00720. eCollection 2014.

Microbiota, the immune system, black moods and the brain-melancholia updated

Lesley E Smythies¹, John R Smythies²

Affiliations

¹ Department of Medicine (Gastroenterology), University of Alabama at Birmingham Birmingham, AL, USA.
² Department of Psychiatry, University of Alabama at Birmingham Birmingham, AL, USA ; Department of Psychology, Center for Brain and Cognition, University of California, San Diego San Diego, CA, USA.

PMID: 25309394
PMCID: PMC4163975
DOI: 10.3389/fnhum.2014.00720

Microbiota, the immune system, black moods and the brain-melancholia updated

Lesley E Smythies et al. Front Hum Neurosci. 2014.

. 2014 Sep 15:8:720.

doi: 10.3389/fnhum.2014.00720. eCollection 2014.

Authors

Lesley E Smythies¹, John R Smythies²

Affiliations

¹ Department of Medicine (Gastroenterology), University of Alabama at Birmingham Birmingham, AL, USA.
² Department of Psychiatry, University of Alabama at Birmingham Birmingham, AL, USA ; Department of Psychology, Center for Brain and Cognition, University of California, San Diego San Diego, CA, USA.

PMID: 25309394
PMCID: PMC4163975
DOI: 10.3389/fnhum.2014.00720

No abstract available

Keywords: MDD; exosomes; gut-brain networks; inflammation; leaky gut hypothesis; microbiota; psychobiotics; stress.

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References

1. Ait-Belgnaoui A., Colom A., Braniste V., Ramalho L., Marrot A., Cartier C., et al. (2014). Probiotic gut effect prevents the chronic psychological stress-induced brain activity abnormality in mice. Neurogastroenterol. Motil. 26, 510–520 10.1111/nmo.12295 - DOI - PubMed
1. Arisi G. M. (2014). Nervous and immune systems signals and connections: cytokines in hippocampus physiology and pathology. Epilepsy Behav. [Epub ahead of print]. 10.1016/j.yebeh.2014.01.017 - DOI - PubMed
1. Bailey M. T., Dowd S. E., Galley J. D., Hufnagle A. R., Allen R. G., Lyte M. (2011). Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain Behav. Immun. 25, 397–407 10.1016/j.bbi.2010.10.023 - DOI - PMC - PubMed
1. Berk M., Williams L. J., Jacka F. N., O'Neil A., Pasco J. A., Moylan S., et al. (2013). So depression is an inflammatory disease, but where does the inflammation come from? BMC Med. 11:200 10.1186/1741-7015-11-200 - DOI - PMC - PubMed
1. Bonaz B. (2013). Inflammatory bowel diseases: a dysfunction of brain-gut interactions? Minerva Gastroenterol. Dietol. 59, 241–259 - PubMed

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[1] Ait-Belgnaoui A., Colom A., Braniste V., Ramalho L., Marrot A., Cartier C., et al. (2014). Probiotic gut effect prevents the chronic psychological stress-induced brain activity abnormality in mice. Neurogastroenterol. Motil. 26, 510–520 10.1111/nmo.12295 - DOI - PubMed

[2] Ait-Belgnaoui A., Colom A., Braniste V., Ramalho L., Marrot A., Cartier C., et al. (2014). Probiotic gut effect prevents the chronic psychological stress-induced brain activity abnormality in mice. Neurogastroenterol. Motil. 26, 510–520 10.1111/nmo.12295 - DOI - PubMed

[3] Arisi G. M. (2014). Nervous and immune systems signals and connections: cytokines in hippocampus physiology and pathology. Epilepsy Behav. [Epub ahead of print]. 10.1016/j.yebeh.2014.01.017 - DOI - PubMed

[4] Arisi G. M. (2014). Nervous and immune systems signals and connections: cytokines in hippocampus physiology and pathology. Epilepsy Behav. [Epub ahead of print]. 10.1016/j.yebeh.2014.01.017 - DOI - PubMed

[5] Bailey M. T., Dowd S. E., Galley J. D., Hufnagle A. R., Allen R. G., Lyte M. (2011). Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain Behav. Immun. 25, 397–407 10.1016/j.bbi.2010.10.023 - DOI - PMC - PubMed

[6] Bailey M. T., Dowd S. E., Galley J. D., Hufnagle A. R., Allen R. G., Lyte M. (2011). Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation. Brain Behav. Immun. 25, 397–407 10.1016/j.bbi.2010.10.023 - DOI - PMC - PubMed

[7] Berk M., Williams L. J., Jacka F. N., O'Neil A., Pasco J. A., Moylan S., et al. (2013). So depression is an inflammatory disease, but where does the inflammation come from? BMC Med. 11:200 10.1186/1741-7015-11-200 - DOI - PMC - PubMed

[8] Berk M., Williams L. J., Jacka F. N., O'Neil A., Pasco J. A., Moylan S., et al. (2013). So depression is an inflammatory disease, but where does the inflammation come from? BMC Med. 11:200 10.1186/1741-7015-11-200 - DOI - PMC - PubMed

[9] Bonaz B. (2013). Inflammatory bowel diseases: a dysfunction of brain-gut interactions? Minerva Gastroenterol. Dietol. 59, 241–259 - PubMed

[10] Bonaz B. (2013). Inflammatory bowel diseases: a dysfunction of brain-gut interactions? Minerva Gastroenterol. Dietol. 59, 241–259 - PubMed

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Microbiota, the immune system, black moods and the brain-melancholia updated

Affiliations

Microbiota, the immune system, black moods and the brain-melancholia updated

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