Update on the antibiotic resistance crisis
- PMID: 25254623
- DOI: 10.1016/j.coph.2014.09.006
Update on the antibiotic resistance crisis
Abstract
Antibiotics tend to lose their efficacy over time due to the emergence and dissemination of resistance among bacterial pathogens. Strains with resistance to multiple antibiotic classes have emerged among major Gram-positive and Gram-negative species including Staphylococcus aureus, Enterococcus spp., Pseudomonas aeruginosa, Acinetobacter spp. Enterobacteriaceae, and Neisseria gonorrhoeae. With some Gram-negatives, resistance may involve most or even all the available antimicrobial options, resulting in extremely drug-resistant or totally drug-resistant phenotypes. This so-called 'antibiotic resistance crisis' has been compounded by the lagging in antibiotic discovery and development programs occurred in recent years, and is jeopardizing the essential role played by antibiotics in current medical practices.
Copyright © 2014 Elsevier Ltd. All rights reserved.
Similar articles
-
Overview perspective of bacterial resistance.Expert Opin Ther Pat. 2010 Oct;20(10):1273-6. doi: 10.1517/13543776.2010.507193. Expert Opin Ther Pat. 2010. PMID: 20687782
-
Antimicrobial activity of tigecycline tested against nosocomial bacterial pathogens from patients hospitalized in the intensive care unit.Diagn Microbiol Infect Dis. 2005 Jul;52(3):203-8. doi: 10.1016/j.diagmicrobio.2005.05.002. Diagn Microbiol Infect Dis. 2005. PMID: 16105565
-
The growing burden of antimicrobial resistance.J Antimicrob Chemother. 2008 Sep;62 Suppl 1:i1-9. doi: 10.1093/jac/dkn241. J Antimicrob Chemother. 2008. PMID: 18684701 Review.
-
Resistance in antimicrobial photodynamic inactivation of bacteria.Photochem Photobiol Sci. 2015 Aug;14(8):1518-26. doi: 10.1039/c5pp00037h. Epub 2015 Jun 22. Photochem Photobiol Sci. 2015. PMID: 26098395
-
Antimicrobial resistance in Europe and its potential impact on empirical therapy.Clin Microbiol Infect. 2008 Dec;14 Suppl 6:2-8. doi: 10.1111/j.1469-0691.2008.02126.x. Clin Microbiol Infect. 2008. PMID: 19040461 Review.
Cited by
-
Antimicrobial susceptibility testing results from 13 hospitals in Viet Nam: VINARES 2016-2017.Antimicrob Resist Infect Control. 2021 May 10;10(1):78. doi: 10.1186/s13756-021-00937-4. Antimicrob Resist Infect Control. 2021. PMID: 33971969 Free PMC article.
-
Multisubstituted pyrimidines effectively inhibit bacterial growth and biofilm formation of Staphylococcus aureus.Sci Rep. 2021 Apr 12;11(1):7931. doi: 10.1038/s41598-021-86852-5. Sci Rep. 2021. PMID: 33846401 Free PMC article.
-
Blue laser light inhibits biofilm formation in vitro and in vivo by inducing oxidative stress.NPJ Biofilms Microbiomes. 2019 Oct 9;5(1):29. doi: 10.1038/s41522-019-0102-9. eCollection 2019. NPJ Biofilms Microbiomes. 2019. PMID: 31602310 Free PMC article.
-
Bloodstream Infections Caused by Multidrug Resistant Bacteria: Clinical and Microbiological Features and Mortality.Sisli Etfal Hastan Tip Bul. 2023 Sep 29;57(3):416-425. doi: 10.14744/SEMB.2023.31697. eCollection 2023. Sisli Etfal Hastan Tip Bul. 2023. PMID: 37900327 Free PMC article.
-
Photocatalytic Protein Damage by Silver Nanoparticles Circumvents Bacterial Stress Response and Multidrug Resistance.mSphere. 2019 May 1;4(3):e00175-19. doi: 10.1128/mSphere.00175-19. mSphere. 2019. PMID: 31043515 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous
