Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Jan 24;385(9965):362-70.
doi: 10.1016/S0140-6736(14)60236-1. Epub 2014 Aug 19.

Maternal and neonatal tetanus

Affiliations
Review

Maternal and neonatal tetanus

C Louise Thwaites et al. Lancet. .

Abstract

Maternal and neonatal tetanus is still a substantial but preventable cause of mortality in many developing countries. Case fatality from these diseases remains high and treatment is limited by scarcity of resources and effective drug treatments. The Maternal and Neonatal Tetanus Elimination Initiative, launched by WHO and its partners, has made substantial progress in eliminating maternal and neonatal tetanus. Sustained emphasis on improvement of vaccination coverage, birth hygiene, and surveillance, with specific approaches in high-risk areas, has meant that the incidence of the disease continues to fall. Despite this progress, an estimated 58,000 neonates and an unknown number of mothers die every year from tetanus. As of June, 2014, 24 countries are still to eliminate the disease. Maintenance of elimination needs ongoing vaccination programmes and improved public health infrastructure.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests

We declare no competing interests.

Figures

Figure 1
Figure 1. Global maternal and neonatal tetanus elimination
Reproduced from reference , by permission of WHO.
Figure 2
Figure 2. Global progress towards maternal and neonatal tetanus elimination
Reproduced from Blencowe and colleagues.

Similar articles

Cited by

References

    1. Roper MH, Vandelaer JH, Gasse FL. Maternal and neonatal tetanus. Lancet. 2007;370:1947–59. - PubMed
    1. Black RE, Cousens S, Johnson HL, et al. and the Child Health Epidemiology Reference Group of WHO and UNICEF Global, regional, and national causes of child mortality in 2008: a systematic analysis. Lancet. 2010;375:1969–87. - PubMed
    1. Rai R, Singh DK. Neonatal tetanus: a continuing challenge. Indian J Pediatr. 2012;79:1648–50. - PubMed
    1. Patel JC, Mehta BC. Tetanus: study of 8,697 cases. Indian J Med Sci. 1999;53:393–401. - PubMed
    1. Chavada VK. To study the clinico-epidemiological factors of tetanus cases admitted in a tertiary care hospital for the last 10 years. J Clin Diagn Res. 2010;4:2649–51.

Publication types

MeSH terms