Age Related Shift in Visceral Fat
Abstract
Fat distribution, especially increased visceral fat, may be as important as overall obesity in increasing risk of heart disease, type 2 diabetes and certain cancers. Risk of disease, as well as visceral fat, increases dramatically with age. Cross-sectional data suggests that increased risk of disease may be largely prevented if the age related increase in visceral fat does not occur. The objective of this short review is to present data that shows visceral fat increasing over 200% in men and 400% in women between the 3rd and 7th decades, show that a combination of weight gain, loss of muscle, and a shift from peripheral to central fat patterning contributes to this increase, and identify hormones that may be responsible for the shift. Finally, the review will show how participation in exercise can slow the age related shift in visceral fat.
Keywords: aerobic training; fat distribution; obesity; resistance training; weight gain.
Conflict of interest statement
No potential conflicts of interest.
Figures
Similar articles
-
Exercise training prevents regain of visceral fat for 1 year following weight loss.Obesity (Silver Spring). 2010 Apr;18(4):690-5. doi: 10.1038/oby.2009.316. Epub 2009 Oct 8. Obesity (Silver Spring). 2010. PMID: 19816413 Free PMC article. Clinical Trial.
-
Visceral adiposity and inflammatory bowel disease.Int J Colorectal Dis. 2021 Nov;36(11):2305-2319. doi: 10.1007/s00384-021-03968-w. Epub 2021 Jun 9. Int J Colorectal Dis. 2021. PMID: 34104989 Review.
-
Exercise and ectopic fat in type 2 diabetes: A systematic review and meta-analysis.Diabetes Metab. 2017 Jun;43(3):195-210. doi: 10.1016/j.diabet.2016.12.006. Epub 2017 Feb 2. Diabetes Metab. 2017. PMID: 28162956 Review.
-
Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trial.Ann Intern Med. 2000 Jul 18;133(2):92-103. doi: 10.7326/0003-4819-133-2-200007180-00008. Ann Intern Med. 2000. PMID: 10896648 Clinical Trial.
-
A dose-response relation between aerobic exercise and visceral fat reduction: systematic review of clinical trials.Int J Obes (Lond). 2007 Dec;31(12):1786-97. doi: 10.1038/sj.ijo.0803683. Epub 2007 Jul 17. Int J Obes (Lond). 2007. PMID: 17637702 Review.
Cited by
-
The impact of body compositions on contrast medium enhancement in chest CT: a randomised controlled trial.BJR Open. 2023 Oct 18;5(1):20230054. doi: 10.1259/bjro.20230054. eCollection 2023. BJR Open. 2023. PMID: 37942494 Free PMC article.
-
Connectedness to Nature Does Not Explain the Variation in Physical Activity and Body Composition in Adults and Older People.Int J Environ Res Public Health. 2021 Nov 14;18(22):11951. doi: 10.3390/ijerph182211951. Int J Environ Res Public Health. 2021. PMID: 34831707 Free PMC article.
-
Anthropometry and bone mineral density in treated and untreated hyperphenylalaninemia.Endocr Connect. 2020 Jul;9(7):649-657. doi: 10.1530/EC-20-0214. Endocr Connect. 2020. PMID: 32520722 Free PMC article.
-
Obesity and Abdominal Obesity in Indian Population: Findings from a Nationally Representative Study of 698,286 Participants.Epidemiologia (Basel). 2023 May 12;4(2):163-172. doi: 10.3390/epidemiologia4020017. Epidemiologia (Basel). 2023. PMID: 37218876 Free PMC article.
-
The interplay of aging, adipose tissue, and COVID-19: a potent alliance with implications for health.Geroscience. 2024 Jun;46(3):2915-2932. doi: 10.1007/s11357-023-01058-z. Epub 2024 Jan 8. Geroscience. 2024. PMID: 38191833 Free PMC article. Review.
References
-
- Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL. Increasing prevalence of overweight among U.S. adults: the National Health and Nutrition Examination Surveys, 1960 to 1991. JAMA. 1994;272:205–212. - PubMed
-
- Eliassen EH, Colditz GA, Rosner B, Willett WC, Hankinson SE. Adult weight change and risk of postmenopausal breast cancer. JAMA. 2006;296:193–201. - PubMed
-
- Colditz GA, Willett WC, Rotnitzky A, Manson JE. Weight gain as a risk factor for clinical diabetes mellitus in women. Annal Intern Med. 1995;122:481–486. - PubMed
-
- Koh-Banerjee P, Wang Y, Hu FB, Spiegelman D, Willettt WC, Rimm EB. Changes in body weight and body fat distribution as risk factors for clinical diabetes in US men. Am J Epidemiol. 2004;159:1150–1159. - PubMed
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous