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Multicenter Study
. 2014 Apr 9:14:46.
doi: 10.1186/1471-2261-14-46.

Determining the prevalence and predictors of sleep disordered breathing in patients with chronic heart failure: rationale and design of the SCHLA-HF registry

Holger Woehrle, Olaf Oldenburg, Michael Arzt  1 , Andrea Graml, Erland Erdmann, Helmut Teschler, Karl Wegscheider; SCHLA-HF Investigators
Affiliations
Multicenter Study

Determining the prevalence and predictors of sleep disordered breathing in patients with chronic heart failure: rationale and design of the SCHLA-HF registry

Holger Woehrle et al. BMC Cardiovasc Disord. .

Abstract

Background: The objective of the SCHLA-HF registry is to investigate the prevalence of sleep-disordered breathing (SDB) in patients with chronic heart failure with reduced left ventricular systolic function (HF-REF) and to determine predictors of SDB in such patients.

Methods: Cardiologists in private practices and in hospitals in Germany are asked to document patients with HF-REF into the prospective SCHLA-HF registry if they meet predefined inclusion and exclusion criteria. Screening was started in October 2007 and enrolment was completed at the end of May 2013. After enrolment in the registry, patients are screened for SDB. SDB screening is mainly undertaken using the validated 2-channel ApneaLink™ device (nasal flow and pulse oximetry; ResMed Ltd., Sydney, Australia). Patients with a significant number of apneas and hypopneas per hour recording time (AHI ≥15/h) and/or clinical symptoms suspicious of SDB will be referred to a cooperating sleep clinic for an attended in-lab polysomnography with certified scoring where the definite diagnosis and, if applicable, the differentiation between obstructive and central sleep apnea will be made. Suggested treatment will be documented.

Discussion: Registries play an important role in facilitating advances in the understanding and management of cardiovascular disease. The SCHLA-HF registry will provide consistent data on a large group of patients with HF-REF that will help to answer questions on the prevalence, risk factors, gender differences and stability of SDB in these patients by cross-sectional analyses. Further insight into the development of SDB will be gained by extension of the registry to include longitudinal data.

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Figures

Figure 1
Figure 1
Patient flow and populations in the SCHLA-HF registry. AHI, apnea-hypopnea index; BMI, body mass index; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association; PG, polygraphy; PSG, polysomnography; SDB, sleep-disordered breathing.
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