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. 2014 Dec 3:55:1-6.
doi: 10.1016/j.pnpbp.2014.01.022. Epub 2014 Mar 1.

Gaining translational momentum: more zebrafish models for neuroscience research

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Gaining translational momentum: more zebrafish models for neuroscience research

Allan V Kalueff et al. Prog Neuropsychopharmacol Biol Psychiatry. .

Abstract

Zebrafish (Danio rerio) are rapidly becoming a popular model organism in translational neuroscience and biological psychiatry research. Here we discuss conceptual, practical and other related aspects of using zebrafish in this field ("from tank to bedside"), and critically evaluate both advantages and limitations of zebrafish models of human brain disorders. We emphasize the need to more actively develop zebrafish models for neuroscience research focusing on complex traits.

Keywords: Animal models; Brain disorders; Translational neuroscience; Zebrafish.

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