Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
- PMID: 2436051
- DOI: 10.1038/326358a0
Three-dimensional structure of a complex of antibody with influenza virus neuraminidase
Abstract
The structure of a complex between influenza virus neuraminidase and an antibody displays features inconsistent with the inflexible 'lock and key' model of antigen-antibody binding. The structure of the antigen changes on binding, and that of the antibody may also change; the interaction therefore has some of the character of a handshake.
Similar articles
-
The neuraminidase of influenza virus.Proteins. 1989;6(4):341-56. doi: 10.1002/prot.340060402. Proteins. 1989. PMID: 2482974 Review.
-
Crystal structure of a peptide complex of anti-influenza peptide antibody Fab 26/9. Comparison of two different antibodies bound to the same peptide antigen.J Mol Biol. 1994 Aug 26;241(4):534-56. doi: 10.1006/jmbi.1994.1530. J Mol Biol. 1994. PMID: 7520084
-
Crystallization and preliminary X-ray analysis of type B influenza virus neuraminidase complexed with antibody Fab fragments.Virology. 1988 Dec;167(2):621-4. Virology. 1988. PMID: 3201756
-
Three-dimensional structures of influenza virus neuraminidase-antibody complexes.Philos Trans R Soc Lond B Biol Sci. 1989 Jun 12;323(1217):511-8. doi: 10.1098/rstb.1989.0028. Philos Trans R Soc Lond B Biol Sci. 1989. PMID: 2569208
-
Idiotypy of anti-influenza virus immune responses.Concepts Immunopathol. 1986;3:233-52. Concepts Immunopathol. 1986. PMID: 2439206 Review. No abstract available.
Cited by
-
An eight-segment swine influenza virus harboring H1 and H3 hemagglutinins is attenuated and protective against H1N1 and H3N2 subtypes in pigs.J Virol. 2013 Sep;87(18):10114-25. doi: 10.1128/JVI.01348-13. Epub 2013 Jul 10. J Virol. 2013. PMID: 23843633 Free PMC article.
-
Insights into neutralization of animal viruses gained from study of influenza virus.Epidemiol Infect. 1991 Apr;106(2):205-20. doi: 10.1017/s0950268800048354. Epidemiol Infect. 1991. PMID: 2019292 Free PMC article. Review. No abstract available.
-
Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.mBio. 2020 Oct 6;11(5):e02315-20. doi: 10.1128/mBio.02315-20. mBio. 2020. PMID: 33024040 Free PMC article.
-
The functional significance of DNA sequence structure in a site-specific genetic recombination reaction.EMBO J. 1988 Jun;7(6):1845-52. doi: 10.1002/j.1460-2075.1988.tb03017.x. EMBO J. 1988. PMID: 3169007 Free PMC article.
-
Mechanism of antigenic variation in an individual epitope on influenza virus N9 neuraminidase.J Virol. 1990 Dec;64(12):5797-803. doi: 10.1128/JVI.64.12.5797-5803.1990. J Virol. 1990. PMID: 1700825 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources