doi: 10.1016/0014-4827(87)90216-3.
Lamins A, B and C share an epitope with the common domain of intermediate filament proteins
- PMID: 2435566
- DOI: 10.1016/0014-4827(87)90216-3
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Lamins A, B and C share an epitope with the common domain of intermediate filament proteins
Exp Cell Res.
1987 Apr.
Abstract
Peripheral lamina were isolated from rat liver nuclei and probed with a monoclonal antibody reactive against a common domain of all intermediate filament (IF) proteins. The antibody reacted against lamins A and C as expected from their known sequence homology with IF proteins. Lamin B was also recognized by the antibody. These results indicate that lamin B, despite important biochemical differences vs lamins A and C, also shares sequence homology with IF proteins.
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