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. 1986 Nov;60(2):813-6.
doi: 10.1128/JVI.60.2.813-816.1986.

The L2 open reading frame of human papillomavirus type 1a encodes a minor structural protein carrying type-specific antigens

C A Komly, F Breitburd, O Croissant, R E Streeck

The L2 open reading frame of human papillomavirus type 1a encodes a minor structural protein carrying type-specific antigens

C A Komly et al. J Virol. 1986 Nov.

Abstract

The proteins encoded by the open reading frames of papillomavirus genomes and the minor polypeptides detected in purified virions are still poorly defined. We show here by its expression in Escherichia coli that the open reading frame L2 of human papillomavirus type 1a codes for a minor structural protein of Mr 76,000. Antisera raised against a truncated L2-beta-galactosidase fusion protein in which the conserved N-terminal region of L2 is missing are type specific for human papillomavirus type 1 virions and are reactive at high dilutions. Expression of the L2-encoded type-specific antigens thus provides a powerful new tool for the identification of papillomaviruses.

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References

    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. Clin Dermatol. 1985 Oct-Dec;3(4):27-42 - PubMed
    1. J Virol. 1977 Oct;24(1):108-20 - PubMed
    1. Virology. 1978 Dec;91(2):243-55 - PubMed
    1. Virology. 1979 Jul 15;96(1):1-8 - PubMed

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