doi: 10.1016/0042-6822(90)90400-l.
Detection and characterization of mumps virus V protein
Affiliations
- PMID: 2389552
- DOI: 10.1016/0042-6822(90)90400-l
Item in Clipboard
Detection and characterization of mumps virus V protein
Virology.
1990 Sep.
Abstract
By cDNA cloning, DNA sequencing, and RNAse mapping analyses two distinct mRNA species were shown to be transcribed from the mumps virus P gene; one faithful and the other edited copies. The former was found to direct the synthesis of the V protein (25K), while the latter, after the addition of two nontemplated G residues, was found to direct the synthesis of the P protein (40K-42K). The carboxy terminal of the V protein contained a cysteine-rich region which was similar but not identical to the metal binding domain motif found in several nucleic acid binding proteins. The V protein was detected not only in mumps virus-infected cells but also in the virions by antiserum raised against a synthetic peptide.
Similar articles
-
Sequence analysis of P gene of human parainfluenza type 2 virus: P and cysteine-rich proteins are translated by two mRNAs that differ by two nontemplated G residues.Virology. 1990 Jul;177(1):116-23. doi: 10.1016/0042-6822(90)90465-4. Virology. 1990. PMID: 2162103
-
Molecular cloning and sequence analysis of the mumps virus gene encoding the P protein: mumps virus P gene is monocistronic.J Gen Virol. 1988 Aug;69 ( Pt 8):2043-9. doi: 10.1099/0022-1317-69-8-2043. J Gen Virol. 1988. PMID: 3404121
-
Sequence analysis of the mumps virus mRNA encoding the P protein.Virology. 1989 Mar;169(1):62-7. doi: 10.1016/0042-6822(89)90041-x. Virology. 1989. PMID: 2922928
-
The mumps virus fusion protein mRNA sequence and homology among the paramyxoviridae proteins.J Gen Virol. 1989 Apr;70 ( Pt 4):801-7. doi: 10.1099/0022-1317-70-4-801. J Gen Virol. 1989. PMID: 2732706
-
A new mumps virus lineage found in the 1995 mumps outbreak in western Switzerland identified by nucleotide sequence analysis of the SH gene.Arch Virol. 1996;141(3-4):733-41. doi: 10.1007/BF01718331. Arch Virol. 1996. PMID: 8645109
Cited by
-
Mumps virus V protein antagonizes interferon without the complete degradation of STAT1.J Virol. 2005 Apr;79(7):4451-9. doi: 10.1128/JVI.79.7.4451-4459.2005. J Virol. 2005. PMID: 15767445 Free PMC article.
-
In vitro transcription and replication of the mumps virus genome.Arch Virol. 1993;128(1-2):177-83. doi: 10.1007/BF01309799. Arch Virol. 1993. PMID: 8418791
-
Characterization of V protein in measles virus-infected cells.J Virol. 1991 Jul;65(7):3421-8. doi: 10.1128/JVI.65.7.3421-3428.1991. J Virol. 1991. PMID: 2041073 Free PMC article.
-
Evolutionary history of cotranscriptional editing in the paramyxoviral phosphoprotein gene.Virus Evol. 2021 Mar 27;7(1):veab028. doi: 10.1093/ve/veab028. eCollection 2021 Jan. Virus Evol. 2021. PMID: 34141448 Free PMC article. Review.
-
Rescue of wild-type mumps virus from a strain associated with recent outbreaks helps to define the role of the SH ORF in the pathogenesis of mumps virus.Virology. 2011 Aug 15;417(1):126-36. doi: 10.1016/j.virol.2011.05.003. Epub 2011 Jun 14. Virology. 2011. PMID: 21676427 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources