Comment
doi: 10.1038/nature12457.
Epub 2013 Jul 24.
Alzheimer's disease: From big data to mechanism
- PMID: 23883924
- PMCID: PMC4409124
- DOI: 10.1038/nature12457
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Comment
Alzheimer's disease: From big data to mechanism
Nature.
.
Abstract
The gene variant APOE4 is the most common genetic risk factor associated with late-onset Alzheimer’s disease. A comprehensive, multilayer study reveals the molecular and cellular signatures of APOE4 in humans.
Comment on
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Integrative genomics identifies APOE ε4 effectors in Alzheimer's disease.Nature. 2013 Aug 1;500(7460):45-50. doi: 10.1038/nature12415. Epub 2013 Jul 24. Nature. 2013. Retraction in: Nature. 2015 Jul 30;523(7562):626. doi: 10.1038/nature14591 PMID: 23883936 Retracted.
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References
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- Rhinn H, et al. Nature. 2013 http://dx.doi.org/10.1038/nature12415. - DOI - PubMed
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- Bettens K, Sleegers K, Van Broeckhoven C. Lancet Neurol. 2013;12:92–104. - PubMed
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