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Review
. 2013 Sep;39(9):931-7.
doi: 10.1016/j.ejso.2013.06.001. Epub 2013 Jun 27.

Peritoneal metastases from colorectal cancer: patient selection for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

S Riss  1 , F Mohamed, S Dayal, T Cecil, A Stift, T Bachleitner-Hofmann, B Moran
Affiliations
Review

Peritoneal metastases from colorectal cancer: patient selection for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

S Riss et al. Eur J Surg Oncol. 2013 Sep.

Abstract

Cytoreductive surgery (CRS) in combination with hyperthermic intraperitoneal chemotherapy (HIPEC) is an established treatment modality for patients with pseudomyxoma peritonei. The majority of patients with pseudomyxoma who have complete tumour removal and HIPEC are cured. Over the last decade CRS for peritoneal metastasis of colorectal origin has emerged as an effective treatment strategy in carefully selected patients. Although convincing evidence is limited, available data shows promising results. The key to a successful outcome is appropriate selection of patients. In patients with extensive peritoneal disease, where complete cytoreduction is not achieved, surgical treatment may not be beneficial and might impair quality of life. In this paper we discuss the challenges of selecting patients with colorectal peritoneal metastases who are likely to benefit from CRS with HIPEC.

Keywords: Colorectal cancer; Cytoreductive surgery; HIPEC; Hyperthermic intraperitoneal chemotherapy; Peritoneal metastases.

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