The effect of cage shelf on the behaviour of male C57BL/6 and BALB/c mice in the elevated plus maze test
- PMID: 23760964
- DOI: 10.1177/0023677213489280
The effect of cage shelf on the behaviour of male C57BL/6 and BALB/c mice in the elevated plus maze test
Abstract
The effect of environmental enrichment in the form of a cage shelf on the behaviour of male C57BL/6 and BALB/c mice was compared. Male C57BL/6 and BALB/c mice were randomly allocated into 12 cages per strain. The mice were kept in control conditions or exposed to a cage shelf for two, four, six or eight weeks, and thereafter assessed with the elevated plus maze. C57BL/6 mice displayed a trend of being less anxious than the BALB/c mice. A cage shelf increased the number of entries made into the open arms and the total number of entries only in the case of the C57BL/6 mice, but had no effect on the behaviour of the BALB/c mice. In conclusion, the effect of a cage shelf on the elevated plus maze behaviour of mice depends on the strain of the animals.
Keywords: cage furniture; elevated plus maze; environmental enrichment; mice; refinement.
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