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. 2013 Mar;10(3):186-7.

doi: 10.1038/nmeth.2369.

Proteoform: a single term describing protein complexity

Lloyd M Smith, Neil L Kelleher; Consortium for Top Down Proteomics

Collaborators

Collaborators

PMID: 23443629
PMCID: PMC4114032
DOI: 10.1038/nmeth.2369

Proteoform: a single term describing protein complexity

Lloyd M Smith et al. Nat Methods. 2013 Mar.

. 2013 Mar;10(3):186-7.

doi: 10.1038/nmeth.2369.

Authors

Lloyd M Smith, Neil L Kelleher; Consortium for Top Down Proteomics

Collaborators

PMID: 23443629
PMCID: PMC4114032
DOI: 10.1038/nmeth.2369

No abstract available

PubMed Disclaimer

Conflict of interest statement

COMPETING FINANCIAL INTERESTS

The authors declare no competing financial interests.

Figures

Figure 1
The origins of the proteoform terminology to cleanly describe biological variability at the level of protein primary structure. UniProt is a gene-centric database, meaning that it strives to have a single accession number for each gene. There are occasional deviations due to multiple genes (in one species) producing precisely the same primary protein sequence in higher eukaryotes. SNP, single-nucleotide polymorphism.

See this image and copyright information in PMC

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