doi: 10.1002/bmb.20650.
Epub 2012 Oct 13.
Proteopedia: 3D visualization and annotation of transcription factor-DNA readout modes
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- PMID: 23166030
- DOI: 10.1002/bmb.20650
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Proteopedia: 3D visualization and annotation of transcription factor-DNA readout modes
Biochem Mol Biol Educ.
2012 Nov-Dec.
Free article
Abstract
3D visualization assists in identifying diverse mechanisms of protein-DNA recognition that can be observed for transcription factors and other DNA binding proteins. We used Proteopedia to illustrate transcription factor-DNA readout modes with a focus on DNA shape, which can be a function of either nucleotide sequence (Hox proteins) or base pairing geometry (p53). © 2012 by The International Union of Biochemistry and Molecular Biology.
Copyright © 2012 Wiley Periodicals, Inc.
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