Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990;11(1):8-25.
doi: 10.1002/cyto.990110104.

A unified model of eukaryotic chromosomes

Affiliations
Free article

A unified model of eukaryotic chromosomes

L Manuelidis et al. Cytometry. 1990.
Free article

Abstract

A revised model of DNA packaging into chromosomes is presented. Its features are consistent with observed structural dimensions and the molecular periodicities related to transcription, replication and matrix attachment domains. The transitions between euchromatic, heterochromatic and metaphase states are explained simply. Molecular and physical properties of chromosomal bands, and their correlation with specific DNA sequence motifs are discussed.

PubMed Disclaimer

Similar articles

Cited by

Publication types

LinkOut - more resources