doi: 10.1016/0006-8993(90)90666-y.
Delayed wallerian degeneration in sciatic nerves of C57BL/Ola mice is associated with impaired regeneration of sensory axons
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- PMID: 2271939
- DOI: 10.1016/0006-8993(90)90666-y
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Delayed wallerian degeneration in sciatic nerves of C57BL/Ola mice is associated with impaired regeneration of sensory axons
Brain Res.
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Abstract
Wallerian degeneration is delayed following sciatic nerve crush in C57BL/Ola mice. Compared to C57BL/6J mice, regeneration of sensory axons is significantly slowed in the Ola mice, but reinnervation does eventually occur. We conclude that Wallerian degeneration is a prerequisite for normal sensory axon regeneration following a crush injury to peripheral nerve.
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