Mesenchymal stromal cells: new directions
- PMID: 22704511
- DOI: 10.1016/j.stem.2012.05.015
Mesenchymal stromal cells: new directions
Erratum in
- Cell Stem Cell. 2012 Jul 6;11(1):136
Abstract
Research into mesenchymal stromal/stem cells (MSCs) has been particularly exciting in the past five years. Our understanding of mechanisms of MSC-mediated tissue regeneration has undergone considerable evolution. Recent investigation of the primary in situ counterpart of cultured MSCs has led to fresh insights into MSC physiology and its role in the immune system. At the same time, the clinical application of MSCs continues to increase markedly. Taken together, a reappraisal of the definition of MSCs, a review of current research directions, and a reassessment of the approach to clinical investigation are timely and prudent.
Copyright © 2012 Elsevier Inc. All rights reserved.
Similar articles
-
The effects of microenvironment in mesenchymal stem cell-based regeneration of intervertebral disc.Spine J. 2013 Mar;13(3):352-62. doi: 10.1016/j.spinee.2012.12.005. Epub 2013 Jan 20. Spine J. 2013. PMID: 23340343 Review.
-
Therapeutic potential and mechanisms of action of mesenchymal stromal cells for Acute Respiratory Distress Syndrome.Curr Stem Cell Res Ther. 2014;9(4):319-29. doi: 10.2174/1574888x09666140228144812. Curr Stem Cell Res Ther. 2014. PMID: 24588087 Review.
-
Approaches to mimic the complexity of the skeletal mesenchymal stem/stromal cell niche in vitro.Eur Cell Mater. 2019 Feb 11;37:88-112. doi: 10.22203/eCM.v037a07. Eur Cell Mater. 2019. PMID: 30742298 Review.
-
Mesenchymal stem cells and bone regeneration: current status.Injury. 2011 Jun;42(6):562-8. doi: 10.1016/j.injury.2011.03.030. Epub 2011 Apr 13. Injury. 2011. PMID: 21489533 Review.
-
Mesenchymal stem cell homing capacity.Transplantation. 2009 May 15;87(9 Suppl):S42-5. doi: 10.1097/TP.0b013e3181a28533. Transplantation. 2009. PMID: 19424004
Cited by
-
Lab-on-Chip Systems for Cell Sorting: Main Features and Advantages of Inertial Focusing in Spiral Microchannels.Micromachines (Basel). 2024 Sep 6;15(9):1135. doi: 10.3390/mi15091135. Micromachines (Basel). 2024. PMID: 39337795 Free PMC article. Review.
-
Involvement of the Wnt/β-catenin signalling pathway in heterotopic ossification and ossification-related diseases.J Cell Mol Med. 2024 Sep;28(18):e70113. doi: 10.1111/jcmm.70113. J Cell Mol Med. 2024. PMID: 39320014 Free PMC article. Review.
-
From mesenchymal stem cells to their extracellular vesicles: Progress and prospects for asthma therapy.Asian J Pharm Sci. 2024 Aug;19(4):100942. doi: 10.1016/j.ajps.2024.100942. Epub 2024 Jul 9. Asian J Pharm Sci. 2024. PMID: 39253613 Free PMC article. Review.
-
Metformin-mediated effects on mesenchymal stem cells and mechanisms: proliferation, differentiation and aging.Front Pharmacol. 2024 Aug 13;15:1465697. doi: 10.3389/fphar.2024.1465697. eCollection 2024. Front Pharmacol. 2024. PMID: 39193338 Free PMC article. Review.
-
Integrated Analysis of Clinical Outcome of Mesenchymal Stem Cell-related Genes in Pan-cancer.Curr Genomics. 2024;25(4):298-315. doi: 10.2174/0113892029291247240422060811. Epub 2024 Apr 26. Curr Genomics. 2024. PMID: 39156727 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous