Review
doi: 10.3851/IMP2125.
The application and mechanism of action of ribavirin in therapy of hepatitis C
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- PMID: 22592135
- PMCID: PMC6271563
- DOI: 10.3851/IMP2125
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Review
The application and mechanism of action of ribavirin in therapy of hepatitis C
Antivir Chem Chemother.
.
Abstract
Ribavirin has been used as an antiviral agent for several decades. Although it has activity against numerous viruses, its major use clinically has been in the treatment of respiratory syncytial virus in paediatric patients and chronic HCV infection in both children and adults. This review highlights the clinical application and mechanism of action of ribavirin and discusses the future role of ribavirin in treatment of HCV where there are intense research efforts to improve therapy.
Conflict of interest statement
Disclosure statement
The authors declare no competing interests.
Figures
Structure of ribavirin and related molecules
Proposed antiviral mechanisms of action of ribavirin
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