Review
doi: 10.1016/0968-0004(90)90230-9.
Embedded or not? Hydrophobic sequences and membranes
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- PMID: 2251726
- DOI: 10.1016/0968-0004(90)90230-9
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Review
Embedded or not? Hydrophobic sequences and membranes
Trends Biochem Sci.
1990 Oct.
Abstract
The same translocation machinery appears to be responsible for both the translocation of soluble proteins across membranes and the insertion of integral membrane proteins into the bilayer. A single mechanism is proposed to accommodate these two functions. This model is also extended to explain the paradoxical translocation of mitochondrial and chloroplastic membrane proteins across one or more membranes before they are finally inserted into their target membranes.
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