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• Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication.

  Guendel I, Iordanskiy S, Van Duyne R, Kehn-Hall K, Saifuddin M, Das R, Jaworski E, Sampey GC, Senina S, Shultz L, Narayanan A, Chen H, Lepene B, Zeng C, Kashanchi F. Guendel I, et al. J Virol. 2014 Jan;88(2):1189-208. doi: 10.1128/JVI.01940-13. Epub 2013 Nov 13. J Virol. 2014. PMID: 24227837 Free PMC article.
• Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.

  Liang SH, Chen JM, Normandin MD, Chang JS, Chang GC, Taylor CK, Trapa P, Plummer MS, Para KS, Conn EL, Lopresti-Morrow L, Lanyon LF, Cook JM, Richter KE, Nolan CE, Schachter JB, Janat F, Che Y, Shanmugasundaram V, Lefker BA, Enerson BE, Livni E, Wang L, Guehl NJ, Patnaik D, Wagner FF, Perlis R, Holson EB, Haggarty SJ, El Fakhri G, Kurumbail RG, Vasdev N. Liang SH, et al. Angew Chem Int Ed Engl. 2016 Aug 8;55(33):9601-5. doi: 10.1002/anie.201603797. Epub 2016 Jun 29. Angew Chem Int Ed Engl. 2016. PMID: 27355874 Free PMC article.
• Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags.

  Litovchick A, Clark MA, Keefe AD. Litovchick A, et al. Artif DNA PNA XNA. 2014;5(1):e27896. doi: 10.4161/adna.27896. Artif DNA PNA XNA. 2014. PMID: 25483841 Free PMC article.
• Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction.

  Pinzi L, Conze C, Bisi N, Torre GD, Soliman A, Monteiro-Abreu N, Trushina NI, Krusenbaum A, Dolouei MK, Hellwig A, Christodoulou MS, Passarella D, Bakota L, Rastelli G, Brandt R. Pinzi L, et al. Nat Commun. 2024 Feb 23;15(1):1679. doi: 10.1038/s41467-024-45851-6. Nat Commun. 2024. PMID: 38396035 Free PMC article.
• N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum.

  Pazicky S, Alder A, Mertens H, Svergun D, Gilberger T, Löw C. Pazicky S, et al. Biochem J. 2022 Feb 11;479(3):337-356. doi: 10.1042/BCJ20210829. Biochem J. 2022. PMID: 35023554 Free PMC article.