Emergence and epidemic occurrence of enterovirus 68 respiratory infections in The Netherlands in 2010
- PMID: 22177700
- DOI: 10.1016/j.virol.2011.11.021
Emergence and epidemic occurrence of enterovirus 68 respiratory infections in The Netherlands in 2010
Abstract
Following an increase in detection of enterovirus 68 (EV68) in community surveillance of respiratory infections in The Netherlands in 2010, epidemiological and virological analyses were performed to investigate the possible public health impact of EV68 infections. We retrospectively tested specimens collected from acute respiratory infections surveillance and through three children cohort studies conducted in The Netherlands from 1994 through 2010. A total of 71 of 13,310 (0.5%) specimens were positive for EV68, of which 67 (94%) were from symptomatic persons. Twenty-four (34%) of the EV68 positive specimens were collected during 2010. EV68-positive patients with respiratory symptoms showed significantly more dyspnea, cough and bronchitis than EV68-negative patients with respiratory symptoms. Phylogenetic analysis showed an increased VP1 gene diversity in 2010, suggesting that the increased number of EV68 detections in 2010 reflects a real epidemic. Clinical laboratories should consider enterovirus diagnostics in the differential diagnosis of patients presenting with respiratory symptoms.
Copyright © 2011 Elsevier Inc. All rights reserved.
Similar articles
-
Upsurge of human enterovirus 68 infections in patients with severe respiratory tract infections.J Clin Virol. 2011 Oct;52(2):103-6. doi: 10.1016/j.jcv.2011.06.019. Epub 2011 Jul 29. J Clin Virol. 2011. PMID: 21802981
-
Acute respiratory infections due to enterovirus 68 in Yamagata, Japan between 2005 and 2010.Microbiol Immunol. 2012 Feb;56(2):139-43. doi: 10.1111/j.1348-0421.2012.00411.x. Microbiol Immunol. 2012. PMID: 22309616
-
September through October 2010 multi-centre study in the Netherlands examining laboratory ability to detect enterovirus 68, an emerging respiratory pathogen.J Virol Methods. 2013 Jun;190(1-2):53-62. doi: 10.1016/j.jviromet.2013.02.010. Epub 2013 Mar 1. J Virol Methods. 2013. PMID: 23458694
-
Global reemergence of enterovirus D68 as an important pathogen for acute respiratory infections.Rev Med Virol. 2015 Mar;25(2):102-14. doi: 10.1002/rmv.1820. Epub 2014 Dec 3. Rev Med Virol. 2015. PMID: 25471236 Free PMC article. Review.
-
Clinical impact and diagnosis of human metapneumovirus infection.Pediatr Infect Dis J. 2004 Jan;23(1 Suppl):S25-32. doi: 10.1097/01.inf.0000108190.09824.e8. Pediatr Infect Dis J. 2004. PMID: 14730267 Review.
Cited by
-
Enterovirus-D68 (EV-D68) in pediatric patients with respiratory infection: The circulation of a new B3 clade in Italy.J Clin Virol. 2018 Feb-Mar;99-100:91-96. doi: 10.1016/j.jcv.2018.01.005. Epub 2018 Jan 12. J Clin Virol. 2018. PMID: 29396353 Free PMC article.
-
Human viral pathogens are pervasive in wastewater treatment center aerosols.J Environ Sci (China). 2018 May;67:45-53. doi: 10.1016/j.jes.2017.07.015. Epub 2017 Jul 29. J Environ Sci (China). 2018. PMID: 29778173 Free PMC article.
-
Recent Clinical Isolates of Enterovirus D68 Have Increased Replication and Induce Enhanced Epithelial Immune Response Compared to the Prototype Fermon Strain.Viruses. 2023 May 31;15(6):1291. doi: 10.3390/v15061291. Viruses. 2023. PMID: 37376591 Free PMC article.
-
Evaluation of a Real-Time Reverse Transcription-PCR Assay for Detection of Enterovirus D68 in Clinical Samples from an Outbreak in New York State in 2014.J Clin Microbiol. 2015 Jun;53(6):1915-20. doi: 10.1128/JCM.00358-15. Epub 2015 Apr 8. J Clin Microbiol. 2015. PMID: 25854481 Free PMC article.
-
Co-circulation of multiple enterovirus D68 subclades, including a novel B3 cluster, across Europe in a season of expected low prevalence, 2019/20.Euro Surveill. 2020 Jan;25(2):1900749. doi: 10.2807/1560-7917.ES.2020.25.2.1900749. Euro Surveill. 2020. PMID: 31964463 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
