doi: 10.1103/PhysRevLett.107.158102.
Epub 2011 Oct 6.
Mössbauer effect in proteins
Affiliations
- PMID: 22107321
- DOI: 10.1103/PhysRevLett.107.158102
Item in Clipboard
Mössbauer effect in proteins
Phys Rev Lett.
.
Abstract
In proteins, the Mössbauer effect and neutron scattering show a broad line and a rapid increase of the conformational mean-square displacement above about 180 K. The increase, dubbed the "dynamical transition," is controversial. We introduce a new interpretation of the Mössbauer effect in proteins and demonstrate that no dynamical transition is required. The increase in the mean-square displacement and the broad line are caused by fluctuations in the protein's hydration shell. Using the dielectric spectrum of these fluctuations, we predict the shape of the Mössbauer spectrum from 80 to 295 K with one dimensionless coefficient.
Similar articles
-
Dynamical transition of myoglobin in a crystal: comparative studies of X-ray crystallography and Mössbauer spectroscopy.Eur Biophys J. 2001 Sep;30(5):319-29. doi: 10.1007/s002490100152. Eur Biophys J. 2001. PMID: 11592689
-
Bulk-solvent and hydration-shell fluctuations, similar to alpha- and beta-fluctuations in glasses, control protein motions and functions.Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14408-13. doi: 10.1073/pnas.0405573101. Epub 2004 Sep 24. Proc Natl Acad Sci U S A. 2004. PMID: 15448207 Free PMC article.
-
Dynamics of hemoglobin investigated by Mössbauer spectroscopy.J Biomol Struct Dyn. 1984 Mar;1(5):1299-309. doi: 10.1080/07391102.1984.10507518. J Biomol Struct Dyn. 1984. PMID: 6400821
-
Proteins in action: the physics of structural fluctuations and conformational changes.Curr Opin Struct Biol. 2003 Oct;13(5):552-7. doi: 10.1016/j.sbi.2003.09.004. Curr Opin Struct Biol. 2003. PMID: 14568609 Review.
-
Mössbauer spectroscopy with a high velocity resolution: advances in biomedical, pharmaceutical, cosmochemical and nanotechnological research.Spectrochim Acta A Mol Biomol Spectrosc. 2013 Jan 1;100:78-87. doi: 10.1016/j.saa.2012.03.020. Epub 2012 Mar 28. Spectrochim Acta A Mol Biomol Spectrosc. 2013. PMID: 22521301 Review.
Cited by
-
Enzyme transient state kinetics in crystal and solution from the perspective of a time-resolved crystallographer.Struct Dyn. 2014 Mar 27;1(2):024701. doi: 10.1063/1.4869472. eCollection 2014 Mar. Struct Dyn. 2014. PMID: 26798774 Free PMC article.
-
The role of momentum transfer during incoherent neutron scattering is explained by the energy landscape model.Proc Natl Acad Sci U S A. 2017 May 16;114(20):5130-5135. doi: 10.1073/pnas.1612267114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461503 Free PMC article.
-
Two Shared Icosahedral Metallacarboranes through Iron: A Joint Experimental and Theoretical Refinement of Mössbauer Spectrum in [Fe(1,2-C2B9H11)2]Cs.ACS Omega. 2023 Apr 7;8(15):13993-14004. doi: 10.1021/acsomega.3c00422. eCollection 2023 Apr 18. ACS Omega. 2023. PMID: 37091389 Free PMC article.
-
Water Determines the Structure and Dynamics of Proteins.Chem Rev. 2016 Jul 13;116(13):7673-97. doi: 10.1021/acs.chemrev.5b00664. Epub 2016 May 17. Chem Rev. 2016. PMID: 27186992 Free PMC article. Review.
-
A wave-mechanical model of incoherent quasielastic scattering in complex systems.Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12764-8. doi: 10.1073/pnas.1411781111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136125 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
