Review
doi: 10.1016/0304-419x(90)90013-q.
The cell biology of transforming growth factor beta
Affiliations
- PMID: 2194569
- DOI: 10.1016/0304-419x(90)90013-q
Item in Clipboard
Review
The cell biology of transforming growth factor beta
Biochim Biophys Acta.
.
Abstract
The TGF beta family of polypeptide growth factors regulates a remarkable diversity of cellular functions, many of which are not directly associated with cell growth. The present review has summarized many of the recent studies that have just begun to conceptually integrate this expanding array of TGF beta functions into the context of a three-dimensional, multicellular organ or tissue, be it normal or diseased. This fascinating research strongly implicates TGF beta as a key modulator of a wide variety of important physiologic and pathophysiologic processes.
Similar articles
-
Transforming growth factor-beta and its actions on cellular growth and differentiation.Curr Top Dev Biol. 1990;24:95-136. Curr Top Dev Biol. 1990. PMID: 2165898 Review.
-
Transforming growth factor beta in the control of epidermal proliferation.Am J Med Sci. 1988 Sep;296(3):159-63. doi: 10.1097/00000441-198809000-00003. Am J Med Sci. 1988. PMID: 2459967 Review.
-
Skeletal tissue and transforming growth factor beta.FASEB J. 1988 Dec;2(15):3066-73. doi: 10.1096/fasebj.2.15.2903838. FASEB J. 1988. PMID: 2903838 Review.
-
Transforming growth factors beta.Br Med Bull. 1989 Apr;45(2):425-37. doi: 10.1093/oxfordjournals.bmb.a072332. Br Med Bull. 1989. PMID: 2557115 Review.
-
Transforming growth factor beta: possible roles in the regulation of normal and leukemic hematopoietic cell growth.J Cell Biochem. 1989 Feb;39(2):175-84. doi: 10.1002/jcb.240390209. J Cell Biochem. 1989. PMID: 2654150 Review.
Cited by
-
Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product.Proc Natl Acad Sci U S A. 1991 Nov 15;88(22):10227-31. doi: 10.1073/pnas.88.22.10227. Proc Natl Acad Sci U S A. 1991. PMID: 1946442 Free PMC article.
-
Regulation of the proportion of insulin cells in embryonic chick pancreas: effect of a growth factor-reduced extracellular matrix in combination with retinoic acid.In Vitro Cell Dev Biol Anim. 2003 May-Jun;39(5-6):196-8. doi: 10.1290/1543-706X(2003)039<0196:ROTPOI>2.0.CO;2. In Vitro Cell Dev Biol Anim. 2003. PMID: 14613334
-
Distinct morphological and mito-inhibitory effects induced by TGF-beta 1, HGF and EGF on mouse, rat and human hepatocytes.Cell Biol Toxicol. 1994 Aug;10(4):219-30. doi: 10.1007/BF00756762. Cell Biol Toxicol. 1994. PMID: 7895151
-
TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes.J Immunol. 2003 Apr 1;170(7):3645-52. doi: 10.4049/jimmunol.170.7.3645. J Immunol. 2003. PMID: 12646629 Free PMC article.
-
Targeted expression of the E6 and E7 oncogenes of human papillomavirus type 16 in the epidermis of transgenic mice elicits generalized epidermal hyperplasia involving autocrine factors.Mol Cell Biol. 1994 Dec;14(12):8250-8. doi: 10.1128/mcb.14.12.8250-8258.1994. Mol Cell Biol. 1994. PMID: 7969162 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
