Introduction to statistical methods to analyze large data sets: principal components analysis

doi:10.1126/scisignal.2001967

Review

. 2011 Sep 6;4(190):tr3.

doi: 10.1126/scisignal.2001967.

Introduction to statistical methods to analyze large data sets: principal components analysis

Neil R Clark¹, Avi Ma'ayan

Affiliations

PMID: 21917717
PMCID: PMC3193798
DOI: 10.1126/scisignal.2001967

Review

Introduction to statistical methods to analyze large data sets: principal components analysis

Neil R Clark et al. Sci Signal. 2011.

. 2011 Sep 6;4(190):tr3.

doi: 10.1126/scisignal.2001967.

Authors

Neil R Clark¹, Avi Ma'ayan

Affiliation

¹ Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.

PMID: 21917717
PMCID: PMC3193798
DOI: 10.1126/scisignal.2001967

Abstract

This Teaching Resource provides lecture notes, slides, and a problem set for a series of lectures from a course entitled "Systems Biology: Biomedical Modeling." The materials are a lecture introducing the mathematical concepts behind principal components analysis (PCA). The lecture describes how to handle large data sets with correlation methods and unsupervised clustering with this popular method of analysis, PCA.

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References

1. Médez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma’ayan A, Enikolopov GN, Frenette PS. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 2010;466:829–834. - PMC - PubMed

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[1] Médez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma’ayan A, Enikolopov GN, Frenette PS. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 2010;466:829–834. - PMC - PubMed

[2] Médez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma’ayan A, Enikolopov GN, Frenette PS. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 2010;466:829–834. - PMC - PubMed

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Introduction to statistical methods to analyze large data sets: principal components analysis

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Introduction to statistical methods to analyze large data sets: principal components analysis

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