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Review
. 2011 Oct;136(4):609-16.
doi: 10.1309/AJCPW0TA8OBBNGCK.

Current and future applications of mass spectrometry to the clinical laboratory

Frederick G Strathmann  1 , Andrew N Hoofnagle
Affiliations
Review

Current and future applications of mass spectrometry to the clinical laboratory

Frederick G Strathmann et al. Am J Clin Pathol. 2011 Oct.

Abstract

Mass spectrometry is an analytic technique with high specificity and a growing presence in laboratory medicine. Various types of mass spectrometers are being used in an increasing number of clinical laboratories around the world, and, as a result, significant improvements in assay performance are occurring rapidly in areas such as toxicology, endocrinology, and biochemical genetics. This review serves as a basic introduction to mass spectrometry, its uses, and associated challenges in the clinical laboratory and ends with a brief discussion of newer methods with the greatest potential for clinical diagnostics.

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