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. 1990 Feb;124(2):331-7.
doi: 10.1093/genetics/124.2.331.

Germ-line and somatic recombination induced by in vitro modified P elements in Drosophila melanogaster

J A Sved  1 , W B Eggleston, W R Engels
Affiliations

Germ-line and somatic recombination induced by in vitro modified P elements in Drosophila melanogaster

J A Sved et al. Genetics. 1990 Feb.

Abstract

The P element insertion delta 2-3(99B) has previously been shown to activate incomplete P elements elsewhere in the genome. We show that this element, in conjunction with a second incomplete P element, P[CaSpeR], also induces recombination in the male germ line. The recombination is induced preferentially in the region of the P[CaSpeR] element. Recombinant chromosomes contain the P[CaSpeR] element in more than 50% of cases, and alternative models of transposon replication and preferential chromosome breakage are put forward to explain this finding. As is the case with male recombination induced by P-M dysgenic crosses, recombination appears to be premeiotic in a high proportion of cases. The delta 2-3(99B) element is known to act in somatic cells. Correspondingly, we show that the delta 2-3(99B)-P[CaSpeR] combination elevates the incidence of somatic recombination.

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