Aging by telomere loss can be reversed
- PMID: 21211774
- DOI: 10.1016/j.stem.2010.12.013
Aging by telomere loss can be reversed
Abstract
Recently in Nature, Jaskelioff et al. (2010) demonstrated that multiple aging phenotypes in a mouse model of accelerated telomere loss can be reversed within 4 weeks of reactivating telomerase. This raises the major question of whether physiological aging, likely caused by a combination of molecular defects, may also be reversible.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.Nature. 2011 Jan 6;469(7328):102-6. doi: 10.1038/nature09603. Epub 2010 Nov 28. Nature. 2011. PMID: 21113150 Free PMC article.
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