Phenol-soluble modulins of Staphylococcus aureus lure neutrophils into battle
- PMID: 20542245
- DOI: 10.1016/j.chom.2010.05.015
Phenol-soluble modulins of Staphylococcus aureus lure neutrophils into battle
Abstract
Epidemics of community-acquired Staphylococcus aureus are caused by strains producing high concentrations of phenol-soluble modulins (PSMs). How neutrophils sense PSMs is revealed in this issue of Cell Host & Microbe. Such interactions are key to infection outcome and may be the basis for development of new treatment strategies.
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Comment on
-
Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus.Cell Host Microbe. 2010 Jun 25;7(6):463-73. doi: 10.1016/j.chom.2010.05.012. Cell Host Microbe. 2010. PMID: 20542250 Free PMC article.
Similar articles
-
Expression and regulation of phenol-soluble modulins and enterotoxins in foodborne Staphylococcus aureus.AMB Express. 2018 Nov 22;8(1):187. doi: 10.1186/s13568-018-0717-x. AMB Express. 2018. PMID: 30467730 Free PMC article.
-
Staphylococcus aureus Phenol-Soluble Modulins α1-α3 Act as Novel Toll-Like Receptor (TLR) 4 Antagonists to Inhibit HMGB1/TLR4/NF-κB Signaling Pathway.Front Immunol. 2018 Apr 25;9:862. doi: 10.3389/fimmu.2018.00862. eCollection 2018. Front Immunol. 2018. PMID: 29922279 Free PMC article.
-
PSM Peptides From Community-Associated Methicillin-Resistant Staphylococcus aureus Impair the Adaptive Immune Response via Modulation of Dendritic Cell Subsets in vivo.Front Immunol. 2019 May 10;10:995. doi: 10.3389/fimmu.2019.00995. eCollection 2019. Front Immunol. 2019. PMID: 31134074 Free PMC article.
-
Phenol-soluble modulins: novel virulence-associated peptides of staphylococci.Future Microbiol. 2014;9(2):203-16. doi: 10.2217/fmb.13.153. Epub 2013 Dec 3. Future Microbiol. 2014. PMID: 24295365 Review.
-
Molecular determinants of staphylococcal biofilm dispersal and structuring.Front Cell Infect Microbiol. 2014 Nov 26;4:167. doi: 10.3389/fcimb.2014.00167. eCollection 2014. Front Cell Infect Microbiol. 2014. PMID: 25505739 Free PMC article. Review.
Cited by
-
Studies on the mechanism of telavancin decreased susceptibility in a laboratory-derived mutant.Microb Drug Resist. 2013 Aug;19(4):247-55. doi: 10.1089/mdr.2012.0195. Epub 2013 Apr 3. Microb Drug Resist. 2013. PMID: 23551248 Free PMC article.
-
Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host Immunity.Front Immunol. 2014 Feb 5;5:37. doi: 10.3389/fimmu.2014.00037. eCollection 2014. Front Immunol. 2014. PMID: 24550921 Free PMC article. Review.
-
Staphylococcus aureus protein A mediates invasion across airway epithelial cells through activation of RhoA GTPase signaling and proteolytic activity.J Biol Chem. 2011 Oct 14;286(41):35891-35898. doi: 10.1074/jbc.M111.295386. Epub 2011 Aug 30. J Biol Chem. 2011. PMID: 21878647 Free PMC article.
-
Characterization of the Human Plasma Biofilm Model (hpBIOM) to Identify Potential Therapeutic Targets for Wound Management of Chronic Infections.Microorganisms. 2024 Jan 26;12(2):269. doi: 10.3390/microorganisms12020269. Microorganisms. 2024. PMID: 38399673 Free PMC article.
-
Global transcriptome analysis of Staphylococcus aureus biofilms in response to innate immune cells.Infect Immun. 2013 Dec;81(12):4363-76. doi: 10.1128/IAI.00819-13. Epub 2013 Sep 16. Infect Immun. 2013. PMID: 24042108 Free PMC article.
Publication types
LinkOut - more resources
Full Text Sources