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. 2010 Apr;16(4):685-7.
doi: 10.3201/eid1604.091278.

Merkel cell polyomavirus in cutaneous swabs

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Merkel cell polyomavirus in cutaneous swabs

Vincent Foulongne et al. Emerg Infect Dis. 2010 Apr.

Abstract

To assess the usefulness of using cutaneous swabs to detect Merkel cell polyomavirus (MCPyV) DNA, we analyzed swabs from persons with Merkel cell carcinoma (MCC), others with skin diseases, and healthy volunteers. MCPyV was detected in at least 1 sample from virtually all participants. Viral loads were higher in samples from patients with MCC.

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Figures

Figure
Figure
Comparison of Merkel cell polyomavirus DNA levels in cutaneous swabs obtained from 46 study participants. A) Patients with Merkel cell carcinoma; B) patients with other skin diseases; C) clinically healthy volunteers. Data are presented as box and whiskers plots. Boxes represent the interquartile range, lines within the boxes represent the median value, and whiskers represent 1.5 × the interquartile range.

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