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. 1978 Jan;25(1):115-23.
doi: 10.1128/JVI.25.1.115-123.1978.

Identification of a 30S RNA with properties of a defective type C virus in murine cells

R S Howk, D H Troxler, D Lowy, P H Duesberg, E M Scolnick

Identification of a 30S RNA with properties of a defective type C virus in murine cells

R S Howk et al. J Virol. 1978 Jan.

Abstract

A novel species of 30S RNA has been detected in a variety of mouse cell lines. The 30S RNA is specifically packaged by helper-independent type C viruses propagated in such cells. Nucleic acid hybridization detects no homology between the 30SRNA and the genomic RNA of helper-independent mouse type C viruses. The properties of the 30S RNA suggest that it is a defective endogenous mouse type C virus and that it is analogous to a previously described class of defective endogenous rat type C virus, which has been shown previously to be the progenitor of Kirsten and Harvey murine sarcoma viruses.

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