Life-threatening bacteraemia in HIV-1 seropositive adults admitted to hospital in Nairobi, Kenya
- PMID: 1975046
- DOI: 10.1016/0140-6736(90)92096-z
Life-threatening bacteraemia in HIV-1 seropositive adults admitted to hospital in Nairobi, Kenya
Abstract
During 6 months, 506 consecutive adult emergency admissions to hospital in Nairobi were enrolled in a study of bacteraemia and HIV infection. 19% were HIV-1 antibody positive. Significantly more HIV-seropositive than seronegative patients had bacteraemia (26% vs 6%). The predominant organisms isolated from the seropositive patients were Salmonella typhimurium and Streptococcus pneumoniae. Mortality was higher in the seropositive than in the seronegative bacteraemic patients. The findings suggest that non-opportunistic bacteria are important causes of morbidity and mortality in HIV-infected individuals in Africa.
Comment in
-
Bacteraemias in HIV-positive patients.Lancet. 1990 Oct 6;336(8719):877-8. Lancet. 1990. PMID: 1976897 No abstract available.
Similar articles
-
Invasive pneumococcal disease in a cohort of predominantly HIV-1 infected female sex-workers in Nairobi, Kenya.Lancet. 1996 Mar 16;347(9003):718-23. doi: 10.1016/s0140-6736(96)90076-8. Lancet. 1996. PMID: 8602001
-
Infection and morbidity in patients with tuberculosis in Nairobi, Kenya.AIDS. 1993 Nov;7(11):1469-74. doi: 10.1097/00002030-199311000-00010. AIDS. 1993. PMID: 8280413
-
Prevalence of human immunodeficiency virus infection: its impact on the diagnostic yields in exudative pleural effusions at the Kenyatta National Hospital, Nairobi.East Afr Med J. 1996 Sep;73(9):575-8. East Afr Med J. 1996. PMID: 8991236
-
The effect of HIV-1 infection during pregnancy and the perinatal period on maternal and child health in Africa.AIDS. 1991;5 Suppl 1:S75-85. AIDS. 1991. PMID: 1669928 Review.
-
Tuberculosis and human immunodeficiency virus infection in developing countries.Lancet. 1990 Feb 17;335(8686):387-90. doi: 10.1016/0140-6736(90)90216-r. Lancet. 1990. PMID: 1968123 Review.
Cited by
-
Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype.Genome Res. 2009 Dec;19(12):2279-87. doi: 10.1101/gr.091017.109. Epub 2009 Nov 9. Genome Res. 2009. PMID: 19901036 Free PMC article.
-
Cotrimoxazole prophylaxis for opportunistic infections in adults with HIV.Cochrane Database Syst Rev. 2003;2003(3):CD003108. doi: 10.1002/14651858.CD003108. Cochrane Database Syst Rev. 2003. PMID: 12917946 Free PMC article. Review.
-
Pseudomonas spp. complications in patients with HIV disease: an eight-year clinical and microbiological survey.Eur J Epidemiol. 2000 Feb;16(2):111-8. doi: 10.1023/a:1007626410724. Eur J Epidemiol. 2000. PMID: 10845259
-
Virulent Salmonella enterica infections can be exacerbated by concomitant infection of the host with a live attenuated S. enterica vaccine via Toll-like receptor 4-dependent interleukin-10 production with the involvement of both TRIF and MyD88.Immunology. 2008 Aug;124(4):469-79. doi: 10.1111/j.1365-2567.2007.02798.x. Epub 2008 Feb 1. Immunology. 2008. PMID: 18217948 Free PMC article.
-
The pattern of bacteraemia in children with severe malaria.Malawi Med J. 2002 Apr;14(1):11-5. Malawi Med J. 2002. PMID: 27528917 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical