doi: 10.1016/0092-8674(77)90295-1.
The early region of SV40 DNA may have more than one gene
- PMID: 196762
- DOI: 10.1016/0092-8674(77)90295-1
Item in Clipboard
The early region of SV40 DNA may have more than one gene
Cell.
1977 Aug.
Abstract
The nucleotide sequence of 70 base pairs (bp) around 0.545 map units (Alu I C and B junction) of the genome from the single Eco RI cleavage site within SV40 DNA is presented. The mRNA transcribed from the early strand template from this stretch contains two copies of the nonsense triplet UAA in each of the three reading frames. Thus at least 25% of the early region of SV40 DNA does not code for the SV40 "A" protein, and the viral contribution to events in the lytic cycle and transformation may be more complex than is generally appreciated.
Similar articles
-
Nucleotide sequence of the restriction fragment Hind-F-EcoRI1 of simian-virus-40 DNA (part of the VP1 gene).Eur J Biochem. 1978 May 16;86(2):317-24. doi: 10.1111/j.1432-1033.1978.tb12313.x. Eur J Biochem. 1978. PMID: 207520
-
Structural changes in simian virus 40 chromatin as probed by restriction endonucleases.J Virol. 1979 Sep;31(3):718-32. doi: 10.1128/JVI.31.3.718-732.1979. J Virol. 1979. PMID: 229248 Free PMC article.
-
Nucleotide sequence about the 3' terminus of SV40 DNA transcripts and the region where DNA synthesis is initiated.Cold Spring Harb Symp Quant Biol. 1975;39 Pt 1:153-60. doi: 10.1101/sqb.1974.039.01.021. Cold Spring Harb Symp Quant Biol. 1975. PMID: 169054 No abstract available.
-
Structure of a large segment of the genome of simian virus 40 that does not encode known proteins.Proc Natl Acad Sci U S A. 1977 Mar;74(3):827-31. doi: 10.1073/pnas.74.3.827. Proc Natl Acad Sci U S A. 1977. PMID: 191835 Free PMC article.
-
Organization and transcription of the simian virus 40 genome.Curr Top Microbiol Immunol. 1979;87:43-172. doi: 10.1007/978-3-642-67344-3_3. Curr Top Microbiol Immunol. 1979. PMID: 232871 Review. No abstract available.
Cited by
-
Nucleotide sequence of the simian virus 40 small-t gene.Proc Natl Acad Sci U S A. 1978 May;75(5):2160-4. doi: 10.1073/pnas.75.5.2160. Proc Natl Acad Sci U S A. 1978. PMID: 209455 Free PMC article.
-
Common methionine-tryptic peptides near the amino-terminal end of primate papovavirus tumor antigens.Proc Natl Acad Sci U S A. 1978 Mar;75(3):1131-5. doi: 10.1073/pnas.75.3.1131. Proc Natl Acad Sci U S A. 1978. PMID: 206886 Free PMC article.
-
Organization and expression of early genes of simian virus 40.Proc Natl Acad Sci U S A. 1978 Jan;75(1):117-21. doi: 10.1073/pnas.75.1.117. Proc Natl Acad Sci U S A. 1978. PMID: 203926 Free PMC article.
-
Spliced early mRNAs of simian virus 40.Proc Natl Acad Sci U S A. 1978 Mar;75(3):1274-8. doi: 10.1073/pnas.75.3.1274. Proc Natl Acad Sci U S A. 1978. PMID: 206891 Free PMC article.
-
Nucleotide sequence of the BK virus DNA segment encoding small t antigen.Proc Natl Acad Sci U S A. 1979 Feb;76(2):565-9. doi: 10.1073/pnas.76.2.565. Proc Natl Acad Sci U S A. 1979. PMID: 218208 Free PMC article.
MeSH terms
Substances
Associated data
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
- Actions
LinkOut - more resources
Full Text Sources
