Liposome triggering of innate immune responses: a perspective on benefits and adverse reactions
- PMID: 19514998
- DOI: 10.1080/08982100902792855
Liposome triggering of innate immune responses: a perspective on benefits and adverse reactions
Abstract
This commentary focuses on therapeutic advantages as well as adverse reactions that entail liposome triggering of the innate immune system, notably the complement cascade and macrophage clearance mechanisms. Our discussion is centered on macrophage drug delivery, evasion of macrophage surveillance, immunogenicity, and hypersensitivity.
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