Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Jun;80(6):882-8.

Marked increase in child survival after four years of intensive malaria control

Immo Kleinschmidt  1 , Christopher Schwabe, Luis Benavente, Miguel Torrez, Frances C Ridl, Jose Luis Segura, Paul Ehmer, Gloria Nseng Nchama
Affiliations

Marked increase in child survival after four years of intensive malaria control

Immo Kleinschmidt et al. Am J Trop Med Hyg. 2009 Jun.

Abstract

In malaria-endemic countries in Africa, a large proportion of child deaths are directly or indirectly attributable to infection with Plasmodium falciparum. Four years after high coverage, multiple malaria control interventions were introduced on Bioko Island, Equatorial Guinea, changes in infection with malarial parasites, anemia, and fever history in children were estimated and assessed in relation to changes in all-cause under-5 mortality. There were reductions in prevalence of infection (odds ratio [OR] = 0.31, 95% confidence interval [CI] = 0.2-0.46), anemia (OR = 0.11, 95% CI = 0.07-0.18), and reported fevers (OR = 0.41, 95% CI = 0.22-0.76) in children. Under-5 mortality fell from 152 per 1,000 births (95% CI = 122-186) to 55 per 1,000 (95% CI = 38-77; hazard ratio = 0.34 [95% CI = 0.23-0.49]). Effective malaria control measures can dramatically increase child survival and play a key role in achieving millennium development goals.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Location of sentinel sites used to monitor the Bioko Island malaria control intervention, 2004 to 2008.
Figure 2
Figure 2
Timing of intervention activities and under five mortality surveys, Bioko, 2004 to 2008.
See this image and copyright information in PMC

Comment in

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. [Accessed August 4, 2008];United Nations Millennium Development Goals. Available at: http://www.un.org/millenniumgoals/index.html.
    1. World Health Organization . The African Summit on Roll Back Malaria, Abuja, Nigeria, 25th April 2000. World Health Organization; Geneva: 2000.
    1. The Global Malaria Action Plan [Accessed March 2, 2009];The Roll Back Malaria Partnership. 2008 Available at: http://www.rbm.who.int/gmap/gmap.pdf.
    1. Rowe AK, Steketee RW. Predictions of the impact of malaria control efforts on all-cause child mortality in sub-Saharan Africa. Am J Trop Med Hyg. 2007;77(Suppl):48–55. - PubMed
    1. Rowe AK, Rowe SY, Snow RW, Korenromp EL, Schellenberg JR, Stein C, Nahlen BL, Bryce J, Black RE, Steketee RW. The burden of malaria mortality among African children in the year 2000. Int J Epidemiol. 2006;35:691–704. - PMC - PubMed

MeSH terms

LinkOut - more resources