doi: 10.1073/pnas.88.22.10004.
The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex
Affiliations
- PMID: 1946417
- PMCID: PMC52855
- DOI: 10.1073/pnas.88.22.10004
Item in Clipboard
The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex
Proc Natl Acad Sci U S A.
.
Abstract
The two forms of RNA polymerase II that exist in vivo, phosphorylated (IIO) and nonphosphorylated (IIA), were purified to apparent homogeneity from HeLa cells. The nonphosphorylated form preferentially binds to the preinitiation complex. RNA polymerase II in the complex was converted by a cellular protein kinase to the phosphorylated form.
Similar articles
-
Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription.J Biol Chem. 1990 Aug 5;265(22):13165-73. J Biol Chem. 1990. PMID: 2376591
-
The transition of RNA polymerase II from initiation to elongation is associated with phosphorylation of the carboxyl-terminal domain of subunit IIa.J Biol Chem. 1989 Nov 25;264(33):19621-9. J Biol Chem. 1989. PMID: 2584185
-
The interaction of RNA polymerase II with the adenovirus-2 major late promoter is precluded by phosphorylation of the C-terminal domain of subunit IIa.J Biol Chem. 1992 May 25;267(15):10500-6. J Biol Chem. 1992. PMID: 1316903
-
Rigorous and quantitative assay of transcription in vitro.Methods Enzymol. 1996;273:86-99. doi: 10.1016/s0076-6879(96)73008-2. Methods Enzymol. 1996. PMID: 8791601 Review. No abstract available.
-
The basics of basal transcription by RNA polymerase II.Cell. 1994 Apr 8;77(1):1-3. doi: 10.1016/0092-8674(94)90226-7. Cell. 1994. PMID: 8156586 Review. No abstract available.
Cited by
-
The non-coding B2 RNA binds to the DNA cleft and active-site region of RNA polymerase II.J Mol Biol. 2013 Oct 9;425(19):3625-38. doi: 10.1016/j.jmb.2013.01.035. Epub 2013 Feb 8. J Mol Biol. 2013. PMID: 23416138 Free PMC article.
-
Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics.bioRxiv [Preprint]. 2024 Oct 10:2024.07.08.602535. doi: 10.1101/2024.07.08.602535. bioRxiv. 2024. Update in: Elife. 2024 Nov 28;13:RP100764. doi: 10.7554/eLife.100764. PMID: 39026809 Free PMC article. Updated. Preprint.
-
A carboxyl-terminal-domain kinase associated with RNA polymerase II transcription factor delta from rat liver.Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7476-80. doi: 10.1073/pnas.89.16.7476. Proc Natl Acad Sci U S A. 1992. PMID: 1386928 Free PMC article.
-
Cross-talk of phosphorylation and prolyl isomerization of the C-terminal domain of RNA Polymerase II.Molecules. 2014 Jan 27;19(2):1481-511. doi: 10.3390/molecules19021481. Molecules. 2014. PMID: 24473209 Free PMC article. Review.
-
Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11167-71. doi: 10.1073/pnas.90.23.11167. Proc Natl Acad Sci U S A. 1993. PMID: 7504297 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
