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• FMNL1 and mDia1 promote efficient T cell migration through complex environments via distinct mechanisms.

  Sigler AL, Thompson SB, Ellwood-Digel L, Kandasamy A, Michaels MJ, Thumkeo D, Narumiya S, Del Alamo JC, Jacobelli J. Sigler AL, et al. Front Immunol. 2024 Oct 4;15:1467415. doi: 10.3389/fimmu.2024.1467415. eCollection 2024. Front Immunol. 2024. PMID: 39430739 Free PMC article.
• A SIRT7-dependent acetylation switch regulates early B cell differentiation and lineage commitment through Pax5.

  Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray JK, Ray C, Berenguer C, Kumari P, Bech JJ, Braun T, Ianni A, Tischfield JA, Serrano L, Esteller M, Sardina JL, De La Torre C, Sigvardsson M, Vazquez BN, Vaquero A. Gamez-Garcia A, et al. Nat Immunol. 2024 Oct 18. doi: 10.1038/s41590-024-01995-7. Online ahead of print. Nat Immunol. 2024. PMID: 39424985
• Sequential responsive nano-PROTACs for precise intracellular delivery and enhanced degradation efficacy in colorectal cancer therapy.

  Yang L, Yang Y, Zhang J, Li M, Yang L, Wang X, Chen M, Zhang H, He B, Wang X, Dai W, Wang Y, Zhang Q. Yang L, et al. Signal Transduct Target Ther. 2024 Oct 18;9(1):275. doi: 10.1038/s41392-024-01983-1. Signal Transduct Target Ther. 2024. PMID: 39419977 Free PMC article.
• Optimization of the Irf8 +32-kb enhancer disrupts dendritic cell lineage segregation.

  Ou F, Liu TT, Desai P, Ferris ST, Kim S, Shen H, Ohara RA, Jo S, Chen J, Postoak JL, Du S, Diamond MS, Murphy TL, Murphy KM. Ou F, et al. Nat Immunol. 2024 Nov;25(11):2043-2056. doi: 10.1038/s41590-024-01976-w. Epub 2024 Oct 7. Nat Immunol. 2024. PMID: 39375550
• Distinctive CD39⁺CD9⁺ lung interstitial macrophages suppress IL-23/Th17-mediated neutrophilic asthma by inhibiting NETosis.

  Han S, Kim B, Hyeon DY, Jeong D, Ryu J, Nam JS, Choi YH, Kim BR, Park SC, Chung YW, Shin SJ, Lee JY, Kim JK, Park J, Lee SW, Kim TB, Cheon JH, Cho HJ, Kim CH, Yoon JH, Hwang D, Ryu JH. Han S, et al. Nat Commun. 2024 Oct 4;15(1):8628. doi: 10.1038/s41467-024-53038-2. Nat Commun. 2024. PMID: 39366998 Free PMC article.