Human T cell development and HIV infection in human hemato-lymphoid system mice
- PMID: 18481457
- DOI: 10.1007/978-3-540-75647-7_8
Human T cell development and HIV infection in human hemato-lymphoid system mice
Abstract
Advances in generation of mice that on human hematopoietic stem and progenitor cell transplantation develop and maintain human hemato-lymphoid cells have fueled an already thriving field of research. We focus here on human T cell development and HIV infection in Rag2 -/- gamma(c) -/- mice transplanted as newborns with human CD34+ cord blood hematopoietic stem and progenitor cells.
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