Recent developments in fragment-based drug discovery
- PMID: 18457385
- DOI: 10.1021/jm8000373
Recent developments in fragment-based drug discovery
Similar articles
-
Structural genomics and drug discovery: all in the family.Curr Opin Chem Biol. 2008 Feb;12(1):32-9. doi: 10.1016/j.cbpa.2008.01.045. Epub 2008 Mar 7. Curr Opin Chem Biol. 2008. PMID: 18282486 Review.
-
Screening for transient biological interactions as applied to albumin ligands: a new concept for drug discovery.Anal Biochem. 2006 Dec 1;359(1):120-3. doi: 10.1016/j.ab.2006.09.007. Epub 2006 Oct 4. Anal Biochem. 2006. PMID: 17052679
-
Using NMR for ligand discovery and optimization.Curr Opin Chem Biol. 2004 Aug;8(4):387-91. doi: 10.1016/j.cbpa.2004.05.002. Curr Opin Chem Biol. 2004. PMID: 15288248 Review.
-
Fragment-based screening using X-ray crystallography and NMR spectroscopy.Curr Opin Chem Biol. 2007 Oct;11(5):485-93. doi: 10.1016/j.cbpa.2007.07.010. Epub 2007 Sep 11. Curr Opin Chem Biol. 2007. PMID: 17851109 Review.
-
Systems biology and systems chemistry: new directions for drug discovery.Chem Biol. 2012 Jan 27;19(1):23-8. doi: 10.1016/j.chembiol.2011.12.012. Chem Biol. 2012. PMID: 22284351 Review.
Cited by
-
Dissecting fragment-based lead discovery at the von Hippel-Lindau protein:hypoxia inducible factor 1α protein-protein interface.Chem Biol. 2012 Oct 26;19(10):1300-12. doi: 10.1016/j.chembiol.2012.08.015. Chem Biol. 2012. PMID: 23102223 Free PMC article.
-
Capturing nature's diversity.PLoS One. 2015 Apr 22;10(4):e0120942. doi: 10.1371/journal.pone.0120942. eCollection 2015. PLoS One. 2015. PMID: 25902039 Free PMC article.
-
Discovery of fragment molecules that bind the human peroxiredoxin 5 active site.PLoS One. 2010 Mar 17;5(3):e9744. doi: 10.1371/journal.pone.0009744. PLoS One. 2010. PMID: 20305821 Free PMC article.
-
Route to three-dimensional fragments using diversity-oriented synthesis.Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6799-804. doi: 10.1073/pnas.1015271108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482811 Free PMC article.
-
Theoretical prediction of hydrogen-bond basicity pKBHX using quantum chemical topology descriptors.J Chem Inf Model. 2014 Feb 24;54(2):553-61. doi: 10.1021/ci400657c. Epub 2014 Feb 4. J Chem Inf Model. 2014. PMID: 24460383 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Chemical Information