Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2009 Mar;20(2):164-71.
doi: 10.1111/j.1399-3038.2008.00742.x. Epub 2008 Mar 10.

Exhaled air temperature in asthmatic children: a mathematical evaluation

Massimo Pifferi  1 , Vincenzo Ragazzo, Antonino Previti, Giovanni Pioggia, Marcello Ferro, Pierantonio Macchia, Giorgio L Piacentini, Attilio L Boner
Affiliations

Exhaled air temperature in asthmatic children: a mathematical evaluation

Massimo Pifferi et al. Pediatr Allergy Immunol. 2009 Mar.

Abstract

Recently, the exhaled breath temperature has been proposed as a potential marker for the evaluation of airway inflammation in asthma. The purpose of this study was to verify the ability to distinguish asthmatics from normal controls by a dedicated detailed mathematical evaluation of the exhaled air curve. Analysis was performed in the different phases of the curve of exhaled temperature, i.e. the rate of temperature increase (Delta e degrees T) and the mean plateau value. Principal components analysis (PCA) and artificial neural networks (ANNs) were used for the evaluation of the data in 90 asthmatic children and in 33 healthy age-matched controls. Both PCA and ANNs showed that a separation between patients and controls can be obtained only by the evaluation of the plateau phase of the curve, which better reflects the periphery of the airway.

PubMed Disclaimer

Comment in

  • Exhaled breath temperature measurement made easy.
    Popov TA, Kralimarkova T, Tzachev C, Dimitrov V, Mun KK, Gill J. Popov TA, et al. Pediatr Allergy Immunol. 2009 Mar;20(2):200-1; author reply 202-3. doi: 10.1111/j.1399-3038.2008.00837.x. Epub 2008 Nov 10. Pediatr Allergy Immunol. 2009. PMID: 19017281 No abstract available.

Similar articles

See all similar articles

Cited by