Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1991 Jun;12(6):189-92.
doi: 10.1016/0167-5699(91)90051-T.

T-cell memory: the connection between function, phenotype and migration pathways

C R Mackay  1
Affiliations
Review

T-cell memory: the connection between function, phenotype and migration pathways

C R Mackay. Immunol Today. 1991 Jun.

Abstract

Immunological memory is a fundamental feature of vertebrate immune systems, providing enhanced protection against previously encountered antigens. The established view has been that immunological memory results from clonal expansion and long-term survival of specialized memory cells. Recently, the nature of memory T cells has come under closer scrutiny because of the ability to distinguish naive and memory T cells phenotypically, particularly in humans. In this article, Charles Mackay discusses three features of memory T cells that help to explain the nature and function of these cells: the increased expression of adhesion and activation molecules on memory T cells, their potent functional status and their specific pathways of recirculation.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

Publication types

LinkOut - more resources