Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation
- PMID: 1817516
- DOI: 10.1515/znc-1991-11-1223
Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation
Abstract
The sedative properties of the essential oil of Lavender (Lavandula angustifolia Miller) and of its main constituents--linalool and linalyl acetate--were investigated in mice followed up in a series of experimental procedures. The significant decrease in the motility of female and male laboratory animals under standardized experimental conditions is found to be closely dependent on the exposure time to the drugs. Nevertheless after an injection of caffeine into mice a hyperactivity was observed which was reduced to nearly a normal motility only by inhalation of these fragrance drugs. In particular the correlation of the motility of the animals to linalool in serum is experimentally proven, thus furnishing evidence of the aromatherapeutical use of herbal pillows employed in folk medicine since ancient times in order to facilitate falling asleep or to minimize stressful situations of man.
Similar articles
-
Antinociceptive and gastroprotective effects of inhaled and orally administered Lavandula hybrida Reverchon "Grosso" essential oil.Life Sci. 2004 Nov 26;76(2):213-23. doi: 10.1016/j.lfs.2004.08.008. Life Sci. 2004. PMID: 15519366
-
Lavender oil lacks natural protection against autoxidation, forming strong contact allergens on air exposure.Contact Dermatitis. 2008 Sep;59(3):143-50. doi: 10.1111/j.1600-0536.2008.01402.x. Contact Dermatitis. 2008. PMID: 18759894
-
Intraplantar injection of bergamot essential oil into the mouse hindpaw: effects on capsaicin-induced nociceptive behaviors.Int Rev Neurobiol. 2009;85:237-48. doi: 10.1016/S0074-7742(09)85018-6. Int Rev Neurobiol. 2009. PMID: 19607974 Review.
-
[Effects of valerian root oil, borneol, isoborneol, bornyl acetate and isobornyl acetate on the motility of laboratory animals (mice) after inhalation].Pharmazie. 1992 Aug;47(8):620-2. Pharmazie. 1992. PMID: 1438515 German.
-
Biosynthesis and therapeutic properties of Lavandula essential oil constituents.Planta Med. 2011 Jan;77(1):7-15. doi: 10.1055/s-0030-1250136. Epub 2010 Jul 21. Planta Med. 2011. PMID: 20665367 Review.
Cited by
-
Physical and psychologic effects of aromatherapy inhalation on pregnant women: a randomized controlled trial.J Altern Complement Med. 2013 Oct;19(10):805-10. doi: 10.1089/acm.2012.0103. Epub 2013 Feb 14. J Altern Complement Med. 2013. PMID: 23410527 Free PMC article. Clinical Trial.
-
Identification of compounds in the essential oil of nutmeg seeds (Myristica fragrans Houtt.) that inhibit locomotor activity in mice.Int J Mol Sci. 2010 Nov 23;11(11):4771-81. doi: 10.3390/ijms11114771. Int J Mol Sci. 2010. PMID: 21151471 Free PMC article.
-
Effects of Drought and Salinity on Two Commercial Varieties of Lavandula angustifolia Mill.Plants (Basel). 2020 May 16;9(5):637. doi: 10.3390/plants9050637. Plants (Basel). 2020. PMID: 32429357 Free PMC article.
-
Relaxing Effects of Breathing Pseudotsuga menziesii and Lavandula angustifolia Essential Oils on Psychophysiological Status in Older Adults.Int J Environ Res Public Health. 2022 Nov 18;19(22):15251. doi: 10.3390/ijerph192215251. Int J Environ Res Public Health. 2022. PMID: 36429972 Free PMC article.
-
Effect of Inhaling Cymbopogon martinii Essential Oil and Geraniol on Serum Biochemistry Parameters and Oxidative Stress in Rats.Biochem Res Int. 2014;2014:493183. doi: 10.1155/2014/493183. Epub 2014 Dec 9. Biochem Res Int. 2014. PMID: 25574396 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical