Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Jan;5(1):16-8.
doi: 10.1038/nmeth1156. Epub 2007 Dec 19.

Next-generation sequencing transforms today's biology

Affiliations
Review

Next-generation sequencing transforms today's biology

Stephan C Schuster. Nat Methods. 2008 Jan.

Abstract

A new generation of non-Sanger-based sequencing technologies has delivered on its promise of sequencing DNA at unprecedented speed, thereby enabling impressive scientific achievements and novel biological applications. However, before stepping into the limelight, next-generation sequencing had to overcome the inertia of a field that relied on Sanger-sequencing for 30 years.

PubMed Disclaimer

Similar articles

  • Primer: Sequencing--the next generation.
    Rusk N, Kiermer V. Rusk N, et al. Nat Methods. 2008 Jan;5(1):15. doi: 10.1038/nmeth1155. Nat Methods. 2008. PMID: 18175411 No abstract available.
  • Sequence census methods for functional genomics.
    Wold B, Myers RM. Wold B, et al. Nat Methods. 2008 Jan;5(1):19-21. doi: 10.1038/nmeth1157. Epub 2007 Dec 19. Nat Methods. 2008. PMID: 18165803 Review.
  • Life from information.
    Voigt CA. Voigt CA. Nat Methods. 2008 Jan;5(1):27-8. doi: 10.1038/nmeth0108-27. Nat Methods. 2008. PMID: 18165804 No abstract available.
  • The year of sequencing.
    Chi KR. Chi KR. Nat Methods. 2008 Jan;5(1):11-4. doi: 10.1038/nmeth1154. Nat Methods. 2008. PMID: 18175410 No abstract available.
  • The expanding scope of DNA sequencing.
    Shendure J, Lieberman Aiden E. Shendure J, et al. Nat Biotechnol. 2012 Nov;30(11):1084-94. doi: 10.1038/nbt.2421. Epub 2012 Nov 8. Nat Biotechnol. 2012. PMID: 23138308 Free PMC article. Review.

Cited by

Publication types

LinkOut - more resources